A novel gene delivery system using EGF receptor-mediated endocytosis

Jiabing Chen; Shinobu Gamou; Atsushi Takayanagi; Nobuyoshi Shimizu

doi:10.1016/0014-5793(94)80357-9

A novel gene delivery system using EGF receptor-mediated endocytosis

Jiabing Chen, Shinobu Gamou, Atsushi Takayanagi, Nobuyoshi Shimizu

研究成果: Article › 査読

106 被引用数 (Scopus)

抄録

A monoclonal antibody to the human epidermal growth factor (EGF) receptor was conjugated with polylysine and the resulting conjugate was affinity-linked with DNA (gene). This novel gene delivery system utilizes receptor-mediated endocytosis and would be especially suitable for gene therapy for EGF receptor-overproducing squamous cell carcinomas.

本文言語	English
ページ（範囲）	167-169
ページ数	3
ジャーナル	FEBS Letters
巻	338
号	2
DOI	https://doi.org/10.1016/0014-5793(94)80357-9
出版ステータス	Published - 1994 1月 31
外部発表	はい

ASJC Scopus subject areas

生物理学
構造生物学
生化学
分子生物学
遺伝学
細胞生物学

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10.1016/0014-5793(94)80357-9

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引用スタイル

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abstract = "A monoclonal antibody to the human epidermal growth factor (EGF) receptor was conjugated with polylysine and the resulting conjugate was affinity-linked with DNA (gene). This novel gene delivery system utilizes receptor-mediated endocytosis and would be especially suitable for gene therapy for EGF receptor-overproducing squamous cell carcinomas.",

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A novel gene delivery system using EGF receptor-mediated endocytosis

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