抄録
The novel monocyclic dienediyne 2, which is a simplified analogue of the neocarzinostatin chromophore (1), was synthesized from D-xylitol via conversion of the keto-aldehyde 13 into the highly strained 10-membered ring compound 14 by a simple intramolecular aldol condensation as the key step. The mode of cycloaromatization of 2 by a thiol addition, reminiscent of the chemistry of 1, was also demonstrated.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 1573-1576 |
| ページ数 | 4 |
| ジャーナル | Tetrahedron Letters |
| 巻 | 35 |
| 号 | 10 |
| DOI | |
| 出版ステータス | Published - 1994 3月 7 |
ASJC Scopus subject areas
- 生化学
- 創薬
- 有機化学