抄録
The novel monocyclic dienediyne 2, which is a simplified analogue of the neocarzinostatin chromophore (1), was synthesized from D-xylitol via conversion of the keto-aldehyde 13 into the highly strained 10-membered ring compound 14 by a simple intramolecular aldol condensation as the key step. The mode of cycloaromatization of 2 by a thiol addition, reminiscent of the chemistry of 1, was also demonstrated.
本文言語 | English |
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ページ(範囲) | 1573-1576 |
ページ数 | 4 |
ジャーナル | Tetrahedron Letters |
巻 | 35 |
号 | 10 |
DOI | |
出版ステータス | Published - 1994 3月 7 |
ASJC Scopus subject areas
- 生化学
- 創薬
- 有機化学