TY - JOUR
T1 - Alcohol drinking patterns have a positive association with cognitive function among older people
T2 - a cross-sectional study
AU - Akagi, Yuya
AU - Kabayama, Mai
AU - Gondo, Yasuyuki
AU - Masui, Yukie
AU - Yasumoto, Saori
AU - Klinpudtan, Nonglak
AU - Srithumsuk, Werayuth
AU - Godai, Kayo
AU - Ikebe, Kazunori
AU - Akasaka, Hiroshi
AU - Yokoyama, Serina
AU - Nozato, Yoichi
AU - Takami, Yoichi
AU - Takeya, Yasushi
AU - Yamamoto, Koichi
AU - Sugimoto, Ken
AU - Arai, Yasumichi
AU - Inagaki, Hiroki
AU - Ishizaki, Tatsuro
AU - Rakugi, Hiromi
AU - Kamide, Kei
N1 - Funding Information:
This study was partially supported by a research grant from the Pfizer Health Research Foundation that was received in 2019 (YA), JSPS KAKENHI 19K11138 (MK), 19K07888 (KK), and Osaka University’s International Joint Research Promotion Program Support Type A (KK).
Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12
Y1 - 2022/12
N2 - Background: The relationship between moderate alcohol drinking or other alcohol drinking patterns such as frequency, beverage type, and situation of drinking and cognitive function is not sufficiently clear in older people. The purpose of this study was to investigate the association between alcohol drinking patterns and cognitive function in community-dwelling Japanese people aged 75 and over. Methods: This study was a cross-sectional design based on a prospective cohort study called the SONIC study. Subjects were older people aged 75-77 or 85-87 who voluntarily participated in 2016-2017. Drinking information was collected for daily drinking frequency, daily drinking intake, beverage type, and non-daily drinking opportunity. Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Other potential confounding factors evaluated were age, sex, medical factors, and psychosocial factors. An analysis of covariance was performed to evaluate the MoCA-J score relative to drinking frequency or alcohol intake. Multiple regression analysis was performed to investigate the association between beverage type or non-daily drinking opportunity and the MoCA-J score. Results: The final number of participants analyzed was 1,226. The MoCA-J score for participants who reported drinking alcohol 1–6 days/week was significantly higher than that for those who reported drinking none or every day. No significant difference in the MoCA-J score was observed relative to daily alcohol intake. In terms of beverage type, wine was associated positively with the MoCA-J score. Non-daily drinking opportunity was also associated positively with the MoCA-J score. Conclusions: Moderate-frequency drinking, wine consumption, and non-daily drinking opportunities were associated with higher cognitive function in community-dwelling Japanese aged 75 and over. Further longitudinal studies are needed to clarify the causal relationships.
AB - Background: The relationship between moderate alcohol drinking or other alcohol drinking patterns such as frequency, beverage type, and situation of drinking and cognitive function is not sufficiently clear in older people. The purpose of this study was to investigate the association between alcohol drinking patterns and cognitive function in community-dwelling Japanese people aged 75 and over. Methods: This study was a cross-sectional design based on a prospective cohort study called the SONIC study. Subjects were older people aged 75-77 or 85-87 who voluntarily participated in 2016-2017. Drinking information was collected for daily drinking frequency, daily drinking intake, beverage type, and non-daily drinking opportunity. Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Other potential confounding factors evaluated were age, sex, medical factors, and psychosocial factors. An analysis of covariance was performed to evaluate the MoCA-J score relative to drinking frequency or alcohol intake. Multiple regression analysis was performed to investigate the association between beverage type or non-daily drinking opportunity and the MoCA-J score. Results: The final number of participants analyzed was 1,226. The MoCA-J score for participants who reported drinking alcohol 1–6 days/week was significantly higher than that for those who reported drinking none or every day. No significant difference in the MoCA-J score was observed relative to daily alcohol intake. In terms of beverage type, wine was associated positively with the MoCA-J score. Non-daily drinking opportunity was also associated positively with the MoCA-J score. Conclusions: Moderate-frequency drinking, wine consumption, and non-daily drinking opportunities were associated with higher cognitive function in community-dwelling Japanese aged 75 and over. Further longitudinal studies are needed to clarify the causal relationships.
KW - Alcohol drinking patterns
KW - Cognitive function
KW - Older people
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UR - http://www.scopus.com/inward/citedby.url?scp=85125432796&partnerID=8YFLogxK
U2 - 10.1186/s12877-022-02852-8
DO - 10.1186/s12877-022-02852-8
M3 - Article
C2 - 35220947
AN - SCOPUS:85125432796
SN - 1471-2318
VL - 22
JO - BMC Geriatrics
JF - BMC Geriatrics
IS - 1
M1 - 158
ER -