An association of actin isoforms with the expression of motile response in pigmentation variants induced from goldfish erythrophoroma cells

Comparison of actin isoforms in unpigmented goldfish cells (a normal dermal fibroblast-like cell line, and an unpigmented erythrophoroma cell line capable of being induced to undergo melanization) and in normal and neoplastic melanized goldfish cells shows that the melanized phenotype is accompanied by the presence of multiple actin isoforms. In contrast, the unpigmented cells have only β-actin. The possible significance of this to pigment organelle translocation is discussed.