Anthraquinone derivatives as a new family of protein photocleavers

Akane Suzuki, Masashi Hasegawa, Maiko Ishii, Shuichi Matsumura, Kazunobu Toshima

研究成果: Article査読

45 被引用数 (Scopus)

抄録

Certain anthraquinones, which are present in many biologically important natural products, effectively and randomly cleaved proteins (BSA or Lyso) during photoirradiation using a long wavelength UV light without any further additives. It was also found that this ability could be improved by the attachment of a suitable substituent into the anthraquinone core skeleton.

本文言語English
ページ(範囲)4624-4627
ページ数4
ジャーナルBioorganic and Medicinal Chemistry Letters
15
20
DOI
出版ステータスPublished - 2005 10月 15

ASJC Scopus subject areas

  • 生化学
  • 分子医療
  • 分子生物学
  • 薬科学
  • 創薬
  • 臨床生化学
  • 有機化学

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