TY - GEN
T1 - Assembly of single adherent cells on mobile microplates
AU - Onoe, Hiroaki
AU - Takeuchi, Shoji
PY - 2008
Y1 - 2008
N2 - This paper describes single-cell-mounted mobile microplates. Microfabricated SiO2 microplates (20-75 μm in diameter and 2 μm in thickness) carry single adherent cells. The microplates are released freely from a plate-holding PDMS substrate. These microplates enabled us to handle adherent cells as if they were floating cells. We applied this cell-handling technique to two types of assembly: (i) microplate-guided 2D assembly of heterogeneous cells for cell-cell interaction analysis, and (ii) 3D microplate assembly powered by cell traction force for fabricating 3D microstructures. These assembly experiments indicate that the cell-mounted mobile microplates make it possible to handle single adherent cells and have potentials to assemble cell-plate microstructures.
AB - This paper describes single-cell-mounted mobile microplates. Microfabricated SiO2 microplates (20-75 μm in diameter and 2 μm in thickness) carry single adherent cells. The microplates are released freely from a plate-holding PDMS substrate. These microplates enabled us to handle adherent cells as if they were floating cells. We applied this cell-handling technique to two types of assembly: (i) microplate-guided 2D assembly of heterogeneous cells for cell-cell interaction analysis, and (ii) 3D microplate assembly powered by cell traction force for fabricating 3D microstructures. These assembly experiments indicate that the cell-mounted mobile microplates make it possible to handle single adherent cells and have potentials to assemble cell-plate microstructures.
UR - https://www.scopus.com/pages/publications/50149104596
UR - https://www.scopus.com/pages/publications/50149104596#tab=citedBy
U2 - 10.1109/MEMSYS.2008.4443652
DO - 10.1109/MEMSYS.2008.4443652
M3 - Conference contribution
AN - SCOPUS:50149104596
SN - 9781424417933
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 300
EP - 303
BT - MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems
T2 - 21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson
Y2 - 13 January 2008 through 17 January 2008
ER -