Assessing patterns of T2/T1rho change in grade 1 cartilage lesions of the distal femur using an angle/layer dependent approach

Yasuhito Kaneko, Taiki Nozaki, Hon Yu, Ran Schwarzkopf, Takeshi Hara, Hiroshi Yoshioka

研究成果: Article査読

5 被引用数 (Scopus)

抄録

Purpose: To assess changes in the patterns of T2 and T1rho values within grade 1 cartilage lesions of osteoarthritis (OA) patients compared to healthy controls. Materials and methods: Twenty healthy knees and 25 OA knees were examined on a 3 T scanner. Areas of signal heterogeneity within the cartilage of the distal femur were identified using fat suppressed proton density-weighted imagines. T2 and T1rho values in each OA patient with grade 1 lesions were compared to average T2 and T1rho values of the corresponding areas in healthy subjects. Results: A total of 28 areas including grade 1 lesion were identified. Compared to normal cartilage, the majority of grade 1 cartilage lesions demonstrated either no significant change or a statistically significant increase in both T2 values (18/28, 64%) and T1rho values (23/28, 82%). Compared to T2, T1rho demonstrated a greater proportion of statistically significantly higher values in OA patients than those from the normal controls. However, T2 and T1rho values in grade 1 lesions can be decreased, or demonstrate mixed patterns compared to those in healthy cartilage. Conclusion: Our results suggest that early degenerative cartilage lesions can demonstrate various patterns of T2 and T1rho changes.

本文言語English
ページ(範囲)201-207
ページ数7
ジャーナルClinical Imaging
50
DOI
出版ステータスPublished - 2018 7月 1
外部発表はい

ASJC Scopus subject areas

  • 放射線学、核医学およびイメージング

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