Azo-tagged C4N4 fluorophores: unusual overcrowded structures and their application to fluorescent imaging

Miki Kohei, Naoki Takizawa, Ryosuke Tsutsumi, Wei Xu, Naoya Kumagai

研究成果: Article査読

抄録

The C4N4 fluorophore is an intense fluorescence emitter featuring a 2,5-diaminopyrimidine core comprising four carbon and four nitrogen atoms. A series of C4N4 derivatives was photochemically dimerized at the 5-amino group, furnishing overcrowded orthotetraaryl-substituted diaryl azo compounds with a characteristic skewed structure revealed by X-ray crystallography. The photo-quenched azo-C4N4s are useful for fluorescently visualizing cells under hypoxic conditions.

本文言語English
ページ(範囲)2889-2893
ページ数5
ジャーナルOrganic and Biomolecular Chemistry
21
14
DOI
出版ステータスPublished - 2023 1月 30

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

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