抄録
Biocatalyst-mediated efficient preparation of highly enantiomerically enriched (R)-5-hexanolide (1) is described. The enantioselective reduction of 5-oxohexanoic acid with Yamadazyma farinosa IFO 10896 and the subseqent lipase-catalyzed kinetic resolution gave (R)-1 in 62% yield with 99.7% e.e.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 983-985 |
| ページ数 | 3 |
| ジャーナル | Synlett |
| 巻 | 1997 |
| 号 | 8 |
| DOI | |
| 出版ステータス | Published - 1997 1月 1 |
ASJC Scopus subject areas
- 有機化学