CO laser angioplasty system: efficacy of manipulatable laser angioscope catheter

Tsunenori Arai, Makoto Kikuchi, Kyoichi M.D. Mizuno, Masami Sakurada, Akira M.D. Miyamoto, Koh Arakawa, Akira Kurita, Haruo M.D. Nakamura, Kiyoshi Takeuchi, Atsushi Utsumi, Yoshiro Akai

研究成果: Conference contribution

1 被引用数 (Scopus)


A percutaneous transluminal coronary angioplasty system using a unique combination of CO laser (5 μm) and As-S infrared glass fiber under the guidance of a manipulatable laser angioscope catheter is described. The ablation and guidance functions of this system are evaluated. The angioplasty treatment procedure under angioscope guidance was studied by in vitro model experiment and in vivo animal experiment. The whole angioplasty system is newly developed. That is, a transportable compact medical CO laser device which can emit up to 10 W, a 5 F manipulatable laser angioscope catheter, a thin CO laser cable of which the diameter is 0.6 mm, an angioscope imaging system for laser ablation guidance, and a system controller were developed. Anesthetized adult mongrel dogs (n = 5) with an artificial complete occlusion in the femoral artery and an artificial human vessel model including occluded or stenotic coronary artery were used. The manipulatability of the catheter was drastically improved (both rotation and bending), therefore, precise control of ablation to expand stenosis was obtained. A 90% artificial stenosis made of human yellow plaque in 4.0 mm diameter in the vessel was expanded to 70% stenosis by repetitive CO laser ablations of which total energy was 220 J. All procedures were performed and controlled under angioscope visualization.

ホスト出版物のタイトルProceedings of SPIE - The International Society for Optical Engineering
出版社Publ by Int Soc for Optical Engineering
出版ステータスPublished - 1992
イベントOptical Fibers in Medicine VII - Los Angeles, CA, USA
継続期間: 1992 1月 211992 1月 22


名前Proceedings of SPIE - The International Society for Optical Engineering


OtherOptical Fibers in Medicine VII
CityLos Angeles, CA, USA

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 凝縮系物理学
  • コンピュータ サイエンスの応用
  • 応用数学
  • 電子工学および電気工学


「CO laser angioplasty system: efficacy of manipulatable laser angioscope catheter」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。