@article{ce9ffb9e368049e59662977fb8d32092,
title = "Coculture of a Pathogenic Actinomycete and Animal Cells to Produce Nocarjamide, a Cyclic Nonapeptide with Wnt Signal-Activating Effect",
abstract = "A coculture method with a pathogenic actinomycete of the genus Nocardia and an animal cell line was designed to reconstruct and emulate the initial infection state, and a new cyclic nonapeptide, named nocarjamide (1), was obtained by coculture of Nocardia tenerifensis IFM 10554T and the mouse macrophage-like cell line J774.1 in a modified Czapek-Dox medium. Nocarjamide (1) exhibited Wnt signal-activating effects.",
author = "Yasumasa Hara and Arai, {Midori A.} and Kazufumi Toume and Hyuma Masu and Tomoyuki Sato and Katsuko Komatsu and Takashi Yaguchi and Masami Ishibashi",
note = "Funding Information: This study was supported by JSPS KAKENHI Grant No. 17H03992 and the Strategic Priority Research Promotion Program of Chiba University, “Phytochemical Plant Molecular Sciences”. Publisher Copyright: Copyright {\textcopyright} 2018 American Chemical Society.",
year = "2018",
month = sep,
day = "21",
doi = "10.1021/acs.orglett.8b02522",
language = "English",
volume = "20",
pages = "5831--5834",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "18",
}