Combined primary aldosteronism and Cushing's syndrome due to a single adrenocortical adenoma complicated by Hashimoto's thyroiditis

Masami Tanaka, Masakazu Izeki, Yasushi Miyazaki, Masayuki Horigome, Takashi Yoneda, Shizuo Tsuyuki, Shigeto Takami, Motohiko Aiba

研究成果: Article査読

17 被引用数 (Scopus)

抄録

A 43-year-old Japanese woman presented hypertension, hypokalemia and typical Cushingoid signs. Autonomous secretion of both aldosterone and cortisol was shown. Abdominal computed tomography demonstrated a single tumor in the right adrenal gland, which established the diagnosis of combined primary aldosteronism and Cushing's syndrome. The resected tumor was a golden yellow-colored adenoma (diameter 4.3 cm) which expressed P450aldo and P45011β, causing oversecretion of both hormones from this adenoma. After tumor resection, overproduction of both hormones disappeared and she developed adrenal insufficiency, suggesting the strong suppression of normal adrenal function. This case was complicated by Hashimoto's thyroiditis.

本文言語English
ページ(範囲)967-971
ページ数5
ジャーナルInternal Medicine
41
11
DOI
出版ステータスPublished - 2002 11月 1
外部発表はい

ASJC Scopus subject areas

  • 内科学

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