Dacryoadenitis associated with Acanthamoeba keratitis

Machiko Tomita, Shigeto Shimmura, Kazuo Tsubota, Jun Shimazaki

研究成果: Article査読

13 被引用数 (Scopus)

抄録

Objective: To report the incidence of dacryoadenitis as a symptom associated with Acanthamoeba keratitis. Methods: We investigated all cases of Acanthamoeba keratitis (20 patients and 21 eyes) diagnosed and treated at Tokyo Dental College, Ichikawa General Hospital, Ichikawa, Japan, between May 1, 1994, and November 30, 2005. We recorded the incidence of dacryoadenitis diagnosed using clinical signs of lacrimal gland swelling and pain on pressure, computed tomography, magnetic resonance imaging, and histopathologic analysis. Results: Eight eyes (38%) of 8 patients had dacryoadenitis simultaneously with Acanthamoeba keratitis. Dacryoadenitis was diagnosed using histopathologic analysis and computed tomography in 1 patient, histopathologic analysis and magnetic resonance imaging in 1, magnetic resonance imaging in 2, and clinical signs alone in 4. Histopathologic examination in 2 patients revealed moderate infiltration of lymphocytes and plasma cells in the lacrimal gland compatible with dacryoadenitis. No Acanthamoeba organisms were found in the lacrimal gland. The standard protocol for Acanthamoeba keratitis was performed without particular treatment of dacryoadenitis in all patients. Lacrimal gland swelling improved after a mean of 10 weeks (range, 4-17 weeks) in conjunction with symptoms of keratitis; however, 1 patient (patient 1) required levator muscle surgery and blepharoplasty for residual ptosis. Conclusion: Dacryoadenitis is a clinical finding associated with Acanthamoeba keratitis.

本文言語English
ページ(範囲)1239-1242
ページ数4
ジャーナルArchives of Ophthalmology
124
9
DOI
出版ステータスPublished - 2006
外部発表はい

ASJC Scopus subject areas

  • 眼科学

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