TY - JOUR
T1 - Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces
T2 - Structure determination
AU - Kakeya, Hideaki
AU - Imoto, Masaya
AU - Takahashil, Yoshikazu
AU - Naganawa, Hiroshi
AU - Takeuchi, Tomio
AU - Umezawa, Kazuo
PY - 1993/7
Y1 - 1993/7
N2 - Dephostatin, a novel tyrosine phosphatase inhibitor, was isolated from the culture broth of Streptomyces sp. MJ742-NF5. The structure was elucidated to be 2-(N-methyl-N-nitroso)hydroquinone by spectral and chemical analyses of dephostatin and its derivatives.
AB - Dephostatin, a novel tyrosine phosphatase inhibitor, was isolated from the culture broth of Streptomyces sp. MJ742-NF5. The structure was elucidated to be 2-(N-methyl-N-nitroso)hydroquinone by spectral and chemical analyses of dephostatin and its derivatives.
UR - http://www.scopus.com/inward/record.url?scp=0027488921&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027488921&partnerID=8YFLogxK
U2 - 10.7164/antibiotics.46.1716
DO - 10.7164/antibiotics.46.1716
M3 - Article
C2 - 8270494
AN - SCOPUS:0027488921
SN - 0021-8820
VL - 46
SP - 1716
EP - 1719
JO - Journal of Antibiotics
JF - Journal of Antibiotics
IS - 11
ER -