抄録
Although there are 23 generic levofloxacin (100 mg) tablets (LVFX tablets) and 1 brand name LVFX tablet (supply now discontinued) in Japan, there have been no reports that have evaluated and compared the dissolution profiles of LVFX tablets using the same dissolution method. We studied the dissolution profile of LVFX tablets by the Paddle method, a standard dissolution test method. Among 23 generic LVFX tablets, 2 LVFX tablets had lower dissolution rates and 14 had higher dissolution rates than the brand name LVFX tablet. It is suggested that LVFX tablets have different dissolution profiles, which could cause different pharmacokinetic profiles.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 996-998 |
| ページ数 | 3 |
| ジャーナル | Journal of Infection and Chemotherapy |
| 巻 | 19 |
| 号 | 5 |
| DOI | |
| 出版ステータス | Published - 2013 10月 |
ASJC Scopus subject areas
- 微生物学（医療）
- 薬理学（医学）
- 感染症
UN SDG
この成果は、次の持続可能な開発目標に貢献しています
