Effect of oxygen plasma treatment on non-thrombogenicity of diamond-like carbon films

S. Nagashima, T. Hasebe, A. Kamijo, Y. Yoshimoto, A. Hotta, H. Morita, H. Terada, M. Tanaka, K. Takahashi, T. Suzuki

研究成果: Article査読

31 被引用数 (Scopus)


The non-thrombogenicity of oxygen-plasma-treated DLC films was investigated as surface coatings for medical devices. DLC films were deposited on polycarbonate substrates by a radio frequency plasma enhanced chemical vapor deposition method using acetylene gas. The deposited DLC films were then treated with plasma of oxygen gas at powers of 15 W, 50 W, and 200 W. Wettability was evaluated by water contact angle measurements and the changes in surface chemistry and roughness were examined by X-ray photoelectron spectroscopy and atomic force microscope analysis, respectively. Each oxygen-plasma-treated DLC film exhibited a hydrophilic nature with water contact angles of 11.1°, 17.7° and 36.8°. The non-thrombogenicity of the samples was evaluated through the incubation with platelet-rich plasma isolated from human whole blood. Non-thrombogenic properties dramatically improved for both 15 W- and 50 W-oxygen-plasma-treated DLC films. These results demonstrate that the oxygen plasma treatment at lower powers promotes the non-thrombogenicity of DLC films with highly hydrophilic surfaces.

ジャーナルDiamond and Related Materials
出版ステータスPublished - 2010 7月

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 化学一般
  • 機械工学
  • 材料化学
  • 電子工学および電気工学


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