TY - JOUR
T1 - Effectiveness of oseltamivir treatment against influenza type A and type B infection in children
AU - Mitamura, Keiko
AU - Sugaya, Norio
AU - Nirasawa, Mari
AU - Shinjoh, Masayoshi
AU - Takeuchi, Yoshinao
N1 - Copyright:
This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PY - 2002/11
Y1 - 2002/11
N2 - We investigated the effectiveness of oseltamivir treatment against influenza virus infection in children. We treated 131 patients (mean age, 5.8 +/- 3.6 years) with oseltamivir (4 mg/kg/day for 5 days) during the 2001-2002 epidemic. All of the patients had been diagnosed with influenza using a rapid diagnosis kit. When treatment was initiated within 48 hours of the onset of fever, 44% of the patients became afebrile (< 37.5 degrees C) within one day, and 86% of them recovered within two days. The average duration of fever after the initiation of oseltamivir treatment was 1.7 days. Oseltamivir was equally effective against both influenza type A and type B. No differences in the effectiveness of oseltamivir treatment were observed between young children (< 4 years of age) and school-aged children (> 6 years of age). No obvious side effects were observed.
AB - We investigated the effectiveness of oseltamivir treatment against influenza virus infection in children. We treated 131 patients (mean age, 5.8 +/- 3.6 years) with oseltamivir (4 mg/kg/day for 5 days) during the 2001-2002 epidemic. All of the patients had been diagnosed with influenza using a rapid diagnosis kit. When treatment was initiated within 48 hours of the onset of fever, 44% of the patients became afebrile (< 37.5 degrees C) within one day, and 86% of them recovered within two days. The average duration of fever after the initiation of oseltamivir treatment was 1.7 days. Oseltamivir was equally effective against both influenza type A and type B. No differences in the effectiveness of oseltamivir treatment were observed between young children (< 4 years of age) and school-aged children (> 6 years of age). No obvious side effects were observed.
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U2 - 10.11150/kansenshogakuzasshi1970.76.946
DO - 10.11150/kansenshogakuzasshi1970.76.946
M3 - Article
C2 - 12508478
AN - SCOPUS:0036877705
SN - 0387-5911
VL - 76
SP - 946
EP - 952
JO - Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases
JF - Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases
IS - 11
ER -