TY - JOUR
T1 - Electroconvulsive Therapy for Patients with Depression Who Lack Capacity for Consent
T2 - Doing Good and Doing No Harm
AU - Takamiya, Akihiro
AU - Bouckaert, Filip
AU - Sienaert, Pascal
AU - Uchida, Takahito
AU - Kudo, Shun
AU - Yamagata, Bun
AU - Kishimoto, Taishiro
AU - Mimura, Masaru
AU - Hirano, Jinichi
N1 - Funding Information:
From the *Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan; and †Neuropsychiatry, Department of Neurosciences, Leuven Brain Institute, ‡Geriatric Psychiatry, and §Academic Center for ECT and Neuromodu-lation (AcCENT), University Psychiatric Center, KU Leuven, Leuven, Belgium. Received for publication November 9, 2020; accepted January 24, 2021. Reprints: Jinichi Hirano, MD, PhD, Department of Neuropsychiatry, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan (e‐mail: hjinichi@keio.jp). The authors have no conflicts of interest or financial disclosures to report. Supported by Japan Agency for Medical Research and Development (AMED) under Grant Number JP20dm0307102h0003. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s Web site (www.ectjournal.com). Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved. DOI: 10.1097/YCT.0000000000000764
Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Objective Electroconvulsive therapy (ECT) is provided in real-world clinical settings for patients lacking capacity for consent. The aim of this study was to investigate the clinical characteristics and clinical effectiveness of ECT in this population. Methods A retrospective chart review was conducted to collect data from patients who received ECT to treat their depressive episodes between April 2012 and March 2019. Differences in clinical characteristics and short-/long-term clinical outcomes between patients who received ECT with their relatives' consent and patients who received ECT by their own consent were examined. The short-/long-term clinical outcomes were determined by clinical global impression scores and readmission rate, respectively. Results Of 168 patients with depressive episodes, 34 (20.2%) received ECT with their relatives' consent. Those patients were older, had lower body mass index, and had shorter episode duration. They also exhibited more frequent psychotic, melancholic, and catatonic features. The main indication for ECT in this population was the need for rapid recovery. Patients lacking capacity for consent showed similar remission (61.8%) and response (82.4%) rates to those with capacity for consent. Readmission rate was not significantly different between groups. Conclusions There were no significant differences in short-/long-term ECT effectiveness between patients with/without capacity for consent. Electroconvulsive therapy is the only established and effective treatment in clinical settings for the most severe cases, wherein patients are incapable of giving consent but need rapid recovery. A general rejection of this practice due to concerns surrounding consent may be unethical under the ethical principles of medical care.
AB - Objective Electroconvulsive therapy (ECT) is provided in real-world clinical settings for patients lacking capacity for consent. The aim of this study was to investigate the clinical characteristics and clinical effectiveness of ECT in this population. Methods A retrospective chart review was conducted to collect data from patients who received ECT to treat their depressive episodes between April 2012 and March 2019. Differences in clinical characteristics and short-/long-term clinical outcomes between patients who received ECT with their relatives' consent and patients who received ECT by their own consent were examined. The short-/long-term clinical outcomes were determined by clinical global impression scores and readmission rate, respectively. Results Of 168 patients with depressive episodes, 34 (20.2%) received ECT with their relatives' consent. Those patients were older, had lower body mass index, and had shorter episode duration. They also exhibited more frequent psychotic, melancholic, and catatonic features. The main indication for ECT in this population was the need for rapid recovery. Patients lacking capacity for consent showed similar remission (61.8%) and response (82.4%) rates to those with capacity for consent. Readmission rate was not significantly different between groups. Conclusions There were no significant differences in short-/long-term ECT effectiveness between patients with/without capacity for consent. Electroconvulsive therapy is the only established and effective treatment in clinical settings for the most severe cases, wherein patients are incapable of giving consent but need rapid recovery. A general rejection of this practice due to concerns surrounding consent may be unethical under the ethical principles of medical care.
KW - capacity for consent
KW - depression
KW - electroconvulsive therapy
KW - medical ethics
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U2 - 10.1097/YCT.0000000000000764
DO - 10.1097/YCT.0000000000000764
M3 - Article
C2 - 33840801
AN - SCOPUS:85114362619
SN - 1095-0680
VL - 37
SP - 171
EP - 175
JO - Journal of ECT
JF - Journal of ECT
IS - 3
ER -