Enhancement of hemostatic ability of dodecapeptide-conjugated phospholipid vesicles by encapsulation of a platelet aggregation-induced factor

Yosuke Okamura; Ippei Maekawa; Makoto Handa; Yasuo Ikeda; Shinji Takeoka

Enhancement of hemostatic ability of dodecapeptide-conjugated phospholipid vesicles by encapsulation of a platelet aggregation-induced factor

Yosuke Okamura, Ippei Maekawa, Makoto Handa, Yasuo Ikeda, Shinji Takeoka

医学部輸血・細胞療法センター

研究成果: Paper › 査読

抄録

We conjugated dodecapeptide (H12); a part of the amino acid sequence of fibrinogen, to the terminal of a part of polyethylenglycol chains which modified the surface of the phospholipids vesicles. In this report, we further encapsulated ADP; platelet aggregation-induced factor in the vesicle to enhance the hemostasis of thrombocytopenic rats.

本文言語	English
ページ数	1
出版ステータス	Published - 2006 10月 19
イベント	55th SPSJ Annual Meeting - Nagoya, Japan 継続期間: 2006 5月 24 → 2006 5月 26

Other

Other	55th SPSJ Annual Meeting
国/地域	Japan
City	Nagoya
Period	06/5/24 → 06/5/26

ASJC Scopus subject areas

工学（全般）

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引用スタイル

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abstract = "We conjugated dodecapeptide (H12); a part of the amino acid sequence of fibrinogen, to the terminal of a part of polyethylenglycol chains which modified the surface of the phospholipids vesicles. In this report, we further encapsulated ADP; platelet aggregation-induced factor in the vesicle to enhance the hemostasis of thrombocytopenic rats.",

keywords = "Dodecapeptide (H12), Haemostatic effect., Phospholipid vesicles, Platelet substitutes, Release property",

author = "Yosuke Okamura and Ippei Maekawa and Makoto Handa and Yasuo Ikeda and Shinji Takeoka",

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T1 - Enhancement of hemostatic ability of dodecapeptide-conjugated phospholipid vesicles by encapsulation of a platelet aggregation-induced factor

AU - Okamura, Yosuke

AU - Maekawa, Ippei

AU - Handa, Makoto

AU - Ikeda, Yasuo

AU - Takeoka, Shinji

PY - 2006/10/19

Y1 - 2006/10/19

N2 - We conjugated dodecapeptide (H12); a part of the amino acid sequence of fibrinogen, to the terminal of a part of polyethylenglycol chains which modified the surface of the phospholipids vesicles. In this report, we further encapsulated ADP; platelet aggregation-induced factor in the vesicle to enhance the hemostasis of thrombocytopenic rats.

AB - We conjugated dodecapeptide (H12); a part of the amino acid sequence of fibrinogen, to the terminal of a part of polyethylenglycol chains which modified the surface of the phospholipids vesicles. In this report, we further encapsulated ADP; platelet aggregation-induced factor in the vesicle to enhance the hemostasis of thrombocytopenic rats.

KW - Dodecapeptide (H12)

KW - Haemostatic effect.

KW - Phospholipid vesicles

KW - Platelet substitutes

KW - Release property

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T2 - 55th SPSJ Annual Meeting

Y2 - 24 May 2006 through 26 May 2006

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