First total synthesis of potent antitumour agent (+)-goniopypyrone

Tony K.M. Shing; Tsui Hon-Chung; Zhou Zhao-Hui

doi:10.1016/S0040-4039(00)61654-4

First total synthesis of potent antitumour agent (+)-goniopypyrone

Tony K.M. Shing, Tsui Hon-Chung, Zhou Zhao-Hui

化学科

研究成果: Article › 査読

27 被引用数 (Scopus)

抄録

The structure and absolute stereochemistry of the natural goniopypyrone is confirmed as 1 by a short and stereoselective synthesis in nine steps from d-glycero-d-gulo-heptono-γ-lactone with an overall yield of 9.7 %.

本文言語	English
ページ（範囲）	691-692
ページ数	2
ジャーナル	Tetrahedron Letters
巻	34
号	4
DOI	https://doi.org/10.1016/S0040-4039(00)61654-4
出版ステータス	Published - 1992 1月 22

ASJC Scopus subject areas

生化学
創薬
有機化学

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10.1016/S0040-4039(00)61654-4

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title = "First total synthesis of potent antitumour agent (+)-goniopypyrone",

abstract = "The structure and absolute stereochemistry of the natural goniopypyrone is confirmed as 1 by a short and stereoselective synthesis in nine steps from d-glycero-d-gulo-heptono-γ-lactone with an overall yield of 9.7 %.",

author = "Shing, {Tony K.M.} and Tsui Hon-Chung and Zhou Zhao-Hui",

year = "1992",

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AU - Zhao-Hui, Zhou

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AB - The structure and absolute stereochemistry of the natural goniopypyrone is confirmed as 1 by a short and stereoselective synthesis in nine steps from d-glycero-d-gulo-heptono-γ-lactone with an overall yield of 9.7 %.

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JO - Tetrahedron Letters

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First total synthesis of potent antitumour agent (+)-goniopypyrone

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