Flavonoids inhibit breast cancer resistance protein-mediated drug resistance: Transporter specificity and structure-activity relationship

Medicine & Life Sciences

• Structure-Activity Relationship 100%
• ATP Binding Cassette Transporter, Subfamily B, Member 1 93%
• Flavonoids 86%
• Drug Resistance 78%
• Breast Neoplasms 54%
• Proteins 31%
• acacetin 11%
• Flavones 9%
• Topotecan 9%
• Mitoxantrone 8%
• ATP-Binding Cassette Transporters 7%
• K562 Cells 7%
• Irinotecan 7%
• Growth 6%
• Antineoplastic Agents 6%
• Inhibitory Concentration 50 5%
• Squamous Cell Carcinoma 5%
• Leukemia 5%
• Fluorescence 5%

Chemical Compounds

• Flavonoid 81%
• Structure-Activity Relationship 73%
• Resistance 53%
• Protein 35%
• SN-38 12%
• Topotecan 12%
• Mitoxantrone 11%
• Cell Growth Inhibition 11%
• Growth Inhibition 9%
• Flavone 9%
• Antineoplastic Agent 6%
• Fluorescence 4%
• Reduction 3%