FSTL1 promotes bone metastasis by causing immune dysfunction

Chie Kudo-Saito

研究成果: Article査読

23 被引用数 (Scopus)

抄録

In spite of significant advances in our understanding of the metastatic process, the relationship between the dissemination of primary neoplasms to the bones and antitumor immunity remains poorly understood. We have recently identified follistatin-like 1 (FSTL1), a soluble protein secreted by snail family zinc finger 1 (SNAI1)-expressing cancer cells, as a key determinant of bone metastasis that operates by inducing a systemic state of immune dysfunction.

本文言語English
論文番号e26528
ジャーナルOncoImmunology
2
11
DOI
出版ステータスPublished - 2013
外部発表はい

ASJC Scopus subject areas

  • 免疫アレルギー学
  • 免疫学
  • 腫瘍学

フィンガープリント

「FSTL1 promotes bone metastasis by causing immune dysfunction」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル