Fundamental electrophysiologic investigation of spinal cord: Refractory period of feline conductive spinal cord evoked potential

Mami Ishikawa, Noriyuki Yamaguchi, Helmut Bertalanffy, Kiyotaka Tamura, Takayuki Ohira, Moriichiro Takase, Takeshi Kawase

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Refractory periods and recovery curves have been used to investigate the physiologic importance and disturbance of peripheral nerves, but the refractory periods of the central nervous system (CNS) have seldom been investigated. We estimated the refractory periods and the recovery curves of the ascending and descending conductive spinal cord evoked potentials (SCEP) in cats. The absolute refractory period of the first and second potentials of both the ascending and descending SCEP was ~0.4-0.5 ms. The amplitudes of the first potentials of the ascending and descending SCEP elicited by test stimuli exhibited significant differences, but their latencies did not differ significantly except at the interstimulus interval (ISI) of 1.5 ms, which implies that the same type of fibers was stimulated in the first potentials of the ascending and descending SCEP. The second potential of the descending SCEP elicited by test stimulus showed > 100% amplitude and a maximal recovery of 200% when the ISI was 3.0 ms. The third potential was produced in the test response more easily when a lower vertebral level (LA) was used as the recording site and the ISI was between 1.0 and 4.0 ms. We consider these phenomena to be the result of elimination of the synaptic inhibitory influence by the conditioning stimulus of the paired stimuli for the descending SCEP.

本文言語English
ページ(範囲)335-344
ページ数10
ジャーナルJournal of Clinical Neurophysiology
14
4
DOI
出版ステータスPublished - 1997

ASJC Scopus subject areas

  • 生理学
  • 神経学
  • 臨床神経学
  • 生理学(医学)

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