"System Design and Management" program, a study that integrates humanities and sciences by crossing many disciplines, is essential to foster talented persons who can lead in the development and operation of large-scale complex systems. A graduate school of this program was established at Keio University in 2008. The subject of the education is large-scale complex technological and social systems, with an education curriculum constructed and practically oriented lecturesprovided such that students can acquire a capacity of system thinking, a design faculty in line with system life cycles and system management abilities. By collaborating with industries and related stakeholders such as domestic and international educational research institutions, we designed an educational curriculum and recruited faculty members, developed educational facilities and research centers, recruited students, provided education, and moreover designed the method ofpublishing accomplishments. As for the establishment of the graduate school in April 2008, the educational curriculum was formed to provide students with opportunities to acquire must-learn capability and knowledge that were classified intosix groups. The validity of the education method was confirmed based on verification of the students' self-evaluation, evaluation by the external evaluation committee and accomplishments by students such as papers, after the first two yearsof graduate education.