Highly efficient conversion of (±)-mandelic acid to its (R)-(-)-enantiomer by combination of enzyme-mediated oxidation and reduction

Shigeo Tsuchiya; Kenji Miyamoto; Hiromichi Ohta

doi:10.1007/BF01027017

Highly efficient conversion of (±)-mandelic acid to its (R)-(-)-enantiomer by combination of enzyme-mediated oxidation and reduction

Shigeo Tsuchiya, Kenji Miyamoto, Hiromichi Ohta

生命情報学科

研究成果: Article › 査読

44 被引用数 (Scopus)

抄録

A novel method for total conversion of racemic mandelic acid into its (R)-enantiomer was developed. The method consists of enantioselective oxidation of (S)-(+)-mandelic acid by Alcaligenes bronchisepticus KU 1201 and NADH-dependent asymmetric reduction of resulting benzoylformic acid to (R)-mandelic acid with cell-free extract of Streptococcus faecalis IFO 12964.

本文言語	English
ページ（範囲）	1137-1142
ページ数	6
ジャーナル	Biotechnology Letters
巻	14
号	12
DOI	https://doi.org/10.1007/BF01027017
出版ステータス	Published - 1992 12月 1

ASJC Scopus subject areas

バイオテクノロジー
バイオエンジニアリング
応用微生物学とバイオテクノロジー

文献へのアクセス

10.1007/BF01027017

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引用スタイル

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