Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives

Tadahiko Mashino; Kumiko Shimotohno; Noriko Ikegami; Dai Nishikawa; Kensuke Okuda; Kyoko Takahashi; Shigeo Nakamura; Masataka Mochizuki

doi:10.1016/j.bmcl.2004.12.030

Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives

Tadahiko Mashino, Kumiko Shimotohno, Noriko Ikegami, Dai Nishikawa, Kensuke Okuda, Kyoko Takahashi, Shigeo Nakamura, Masataka Mochizuki

薬科学科

研究成果: Article › 査読

172 被引用数 (Scopus)

抄録

We examined the human immunodeficiency virus-reverse transcriptase and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of cationic, anionic, and amino acid-type fullerene derivatives. Among the fullerene derivatives, the amino acid-type fullerene derivative was the most efficient in human immunodeficiency virus-reverse transcriptase inhibition.

本文言語	English
ページ（範囲）	1107-1109
ページ数	3
ジャーナル	Bioorganic and Medicinal Chemistry Letters
巻	15
号	4
DOI	https://doi.org/10.1016/j.bmcl.2004.12.030
出版ステータス	Published - 2005 2月 15

ASJC Scopus subject areas

生化学
分子医療
分子生物学
薬科学
創薬
臨床生化学
有機化学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

文献へのアクセス

10.1016/j.bmcl.2004.12.030

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引用スタイル

Mashino, T., Shimotohno, K., Ikegami, N., Nishikawa, D., Okuda, K., Takahashi, K., Nakamura, S., & Mochizuki, M. (2005). Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives. Bioorganic and Medicinal Chemistry Letters, 15(4), 1107-1109. https://doi.org/10.1016/j.bmcl.2004.12.030

Mashino, T, Shimotohno, K, Ikegami, N, Nishikawa, D, Okuda, K, Takahashi, K, Nakamura, S & Mochizuki, M 2005, 'Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives', Bioorganic and Medicinal Chemistry Letters, vol. 15, no. 4, pp. 1107-1109. https://doi.org/10.1016/j.bmcl.2004.12.030

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abstract = "We examined the human immunodeficiency virus-reverse transcriptase and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of cationic, anionic, and amino acid-type fullerene derivatives. Among the fullerene derivatives, the amino acid-type fullerene derivative was the most efficient in human immunodeficiency virus-reverse transcriptase inhibition.",

keywords = "Anti-HCV, Anti-HIV, Fullerene, RNA-dependent RNA polymerase, Reverse transcriptase",

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note = "Funding Information: This work was supported in part by a grant from the Science Research Promotion Fund of the Japan Private School Promotion Foundation and by the Mochida Memorial Foundation for Medical and Pharmaceutical Research.",

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AU - Mashino, Tadahiko

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AU - Nishikawa, Dai

AU - Okuda, Kensuke

AU - Takahashi, Kyoko

AU - Nakamura, Shigeo

AU - Mochizuki, Masataka

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KW - Anti-HIV

KW - Fullerene

KW - RNA-dependent RNA polymerase

KW - Reverse transcriptase

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