Importance of skin perfusion pressure in treatment of critical limb ischemiai

Yoriko Tsuji, Terashi Hiroto, Ikuro Kitano, Shinya Tahara, Daisuke Sugiyama

研究成果: Article査読

23 被引用数 (Scopus)


The authors studied whether skin perfusion pressure (SPP) measurements can be used to accurately predict wound healing in critical limb ischemia (CLI) and to select peripheral arterial reconstructive procedures. Methods. Forty-seven patients (33 men and 14 women, age 36ĝ€"83 years) with 69 ischemic limbs with foot ulcers or gangrene were studied retrospectively. Skin perfusion pressure was compared to the treatment outcomes (ulcers healed and ulcers that failed to heal). As a diagnostic test for CLI, the sensitivity, specificity, and the positive and the negative predictive values (PPV, NPV) of SPP measurement were calculated; the data was then analyzed by the receiver operation characteristic (ROC) curve. Results. According to the ROC curve, the best SPP measurement performance was at 35 mmHg. Conclusion. Wound healing at the appropriate amputation level must be predicted to minimize invasive debridement. Skin perfusion pressure measurement is useful for predicting wound healing in the presence of CLI. Skin perfusion pressure ĝ‰¥ 35 mmHg is requisite for wound healing; at SPP <35 mmHg, peripheral arterial reconstruction is necessary before debridement.

出版ステータスPublished - 2008 4月

ASJC Scopus subject areas

  • 外科
  • 外科医療


「Importance of skin perfusion pressure in treatment of critical limb ischemiai」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。