In Situ Generation of Ruthenium Carbonyl Phosphine Complexes as a Versatile Method for the Development of Enantioselective C−O Bond Arylation

Hikaru Kondo; Takuya Kochi; Fumitoshi Kakiuchi

doi:10.1002/chem.201905157

In Situ Generation of Ruthenium Carbonyl Phosphine Complexes as a Versatile Method for the Development of Enantioselective C−O Bond Arylation

Hikaru Kondo, Takuya Kochi, Fumitoshi Kakiuchi

化学科

研究成果: Article › 査読

5 被引用数 (Scopus)

抄録

We report here a method for in situ generation of various ruthenium carbonyl phosphine catalysts for arylation via cleavage of inert aromatic carbon–oxygen bonds. The use of catalyst systems consisting of [RuCl₂(CO)(p-cymene)], CsF, styrene, and phosphines enabled facile screening of phosphine ligands. Asymmetric C–O arylation was also achieved for atropo-enantioselective biaryl synthesis using a chiral monodentate phosphine ligand.

本文言語	English
ページ（範囲）	1737-1741
ページ数	5
ジャーナル	Chemistry - A European Journal
巻	26
号	8
DOI	https://doi.org/10.1002/chem.201905157
出版ステータス	Published - 2020 2月 6

ASJC Scopus subject areas

触媒
有機化学

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10.1002/chem.201905157

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引用スタイル

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abstract = "We report here a method for in situ generation of various ruthenium carbonyl phosphine catalysts for arylation via cleavage of inert aromatic carbon–oxygen bonds. The use of catalyst systems consisting of [RuCl2(CO)(p-cymene)], CsF, styrene, and phosphines enabled facile screening of phosphine ligands. Asymmetric C–O arylation was also achieved for atropo-enantioselective biaryl synthesis using a chiral monodentate phosphine ligand.",

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KW - cleavage reactions

KW - homogeneous catalysis

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