抄録
We developed pDNA/chitosan complexes coated with sugar-modified PEG-A/Cs, which are poly(ethylene glycol) derivatives with a side chain of carboxylic acid and sugar. The cationic pDNA/chitosan complexes were coated with anionic sugar-modified PEG-Cs, and anionic ternary complexes were formed. Coating the pDNA/chitosan complexes with maltose-or lactose-modified PEG-A/C (Mal-PEG-A/C or Lac-PEG-A/C, respectively) greatly promoted their stability in water and transfection efficiency in vitro.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 266-267 |
| ページ数 | 2 |
| ジャーナル | Chemistry Letters |
| 巻 | 37 |
| 号 | 3 |
| DOI | |
| 出版ステータス | Published - 2008 3月 5 |
ASJC Scopus subject areas
- 化学 (全般)