Ion concentration measurement using synthetic microfluidic papers

Haruka Kamiya, Hiroki Yasuga, Norihisa Miki

研究成果: Article査読

3 被引用数 (Scopus)


Non-invasive diagnosis on biological liquid samples, such as urine, sweat, saliva, and tears, may allow patients to evaluate their health by themselves. To obtain accurate diagnostic results, target liquid must be precisely sampled. Conventionally, urine sampling using filter paper can be given as an example sampling, but differences in the paper structure can cause variations in sampling volume. This paper describes precise liquid sampling using synthetic microfluidic papers, which are composed of obliquely combined micropillars. Sampling volume accuracy was investigated using different designs and collection methods to determine the optimal design and sample collecting method. The optimized protocol was followed to accurately measure potassium concentration using synthetic microfluidic paper and a commercially available densitometer, which verified the usefulness of the synthetic microfluidic papers for precision sampling.

ジャーナルPloS one
11 November
出版ステータスPublished - 2020 11月

ASJC Scopus subject areas

  • 生化学、遺伝学、分子生物学(全般)
  • 農業および生物科学(全般)
  • 一般


「Ion concentration measurement using synthetic microfluidic papers」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。