Islet Cell Tumor in von Hippel-Lindau Disease

Nobumasa Mizlno; Satoru Naruse; Motoji Kitagawa; Hiroshi Ishiguro; Yasuyuki Nakak; Hideaki Ihda; Naohiko Iizuka; Osamu Ito; Yasunaga Seki; Shigeru B.H. Ko; Toshiyuki Yoshikawa; Tetsuo Hayakawa; Tsuyoshi Sano; Junichi Kamiya; Yuji Nimura; Tetsuro Nagasaka

doi:10.2169/internalmedicine.37.295

Islet Cell Tumor in von Hippel-Lindau Disease

Nobumasa Mizlno, Satoru Naruse, Motoji Kitagawa, Hiroshi Ishiguro, Yasuyuki Nakak, Hideaki Ihda, Naohiko Iizuka, Osamu Ito, Yasunaga Seki, Shigeru B.H. Ko, Toshiyuki Yoshikawa, Tetsuo Hayakawa, Tsuyoshi Sano, Junichi Kamiya, Yuji Nimura, Tetsuro Nagasaka

研究成果: Article › 査読

4 被引用数 (Scopus)

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We describe a 42-year-old man with von Hippel-Lindau disease and islet cell tumor of the pancreas. He had retinal and cerebellar hemangioblastomas. His sister had pheochromocytoma. A pancreatic tumor was detected by ultrasonography at his periodical medical checkup. Contrast enhanced computed tomography and abdominal angiography revealed a hypervascular tumor in the pancreatic head. Histological examination of the resected tumor revealed characteristics of islet cell tumor of the pancreas, which was positive for chromogranin- A, S-100 protein, and pancreatic polypeptide, but was negative for insulin, gastrin, glucagon, somatostatin, vasoactive intestinal peptide, serotonin, and adrenocorticotropic hormone.

本文言語	English
ページ（範囲）	295-299
ページ数	5
ジャーナル	Internal Medicine
巻	37
号	3
DOI	https://doi.org/10.2169/internalmedicine.37.295
出版ステータス	Published - 1998
外部発表	はい

ASJC Scopus subject areas

内科学

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10.2169/internalmedicine.37.295

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title = "Islet Cell Tumor in von Hippel-Lindau Disease",

abstract = "We describe a 42-year-old man with von Hippel-Lindau disease and islet cell tumor of the pancreas. He had retinal and cerebellar hemangioblastomas. His sister had pheochromocytoma. A pancreatic tumor was detected by ultrasonography at his periodical medical checkup. Contrast enhanced computed tomography and abdominal angiography revealed a hypervascular tumor in the pancreatic head. Histological examination of the resected tumor revealed characteristics of islet cell tumor of the pancreas, which was positive for chromogranin- A, S-100 protein, and pancreatic polypeptide, but was negative for insulin, gastrin, glucagon, somatostatin, vasoactive intestinal peptide, serotonin, and adrenocorticotropic hormone.",

keywords = "Hemangioblastoma, Pancreatic polypeptide producing tumor",

author = "Nobumasa Mizlno and Satoru Naruse and Motoji Kitagawa and Hiroshi Ishiguro and Yasuyuki Nakak and Hideaki Ihda and Naohiko Iizuka and Osamu Ito and Yasunaga Seki and Ko, {Shigeru B.H.} and Toshiyuki Yoshikawa and Tetsuo Hayakawa and Tsuyoshi Sano and Junichi Kamiya and Yuji Nimura and Tetsuro Nagasaka",

year = "1998",

doi = "10.2169/internalmedicine.37.295",

language = "English",

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pages = "295--299",

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T1 - Islet Cell Tumor in von Hippel-Lindau Disease

AU - Mizlno, Nobumasa

AU - Naruse, Satoru

AU - Kitagawa, Motoji

AU - Ishiguro, Hiroshi

AU - Nakak, Yasuyuki

AU - Ihda, Hideaki

AU - Iizuka, Naohiko

AU - Ito, Osamu

AU - Seki, Yasunaga

AU - Ko, Shigeru B.H.

AU - Yoshikawa, Toshiyuki

AU - Hayakawa, Tetsuo

AU - Sano, Tsuyoshi

AU - Kamiya, Junichi

AU - Nimura, Yuji

AU - Nagasaka, Tetsuro

PY - 1998

Y1 - 1998

N2 - We describe a 42-year-old man with von Hippel-Lindau disease and islet cell tumor of the pancreas. He had retinal and cerebellar hemangioblastomas. His sister had pheochromocytoma. A pancreatic tumor was detected by ultrasonography at his periodical medical checkup. Contrast enhanced computed tomography and abdominal angiography revealed a hypervascular tumor in the pancreatic head. Histological examination of the resected tumor revealed characteristics of islet cell tumor of the pancreas, which was positive for chromogranin- A, S-100 protein, and pancreatic polypeptide, but was negative for insulin, gastrin, glucagon, somatostatin, vasoactive intestinal peptide, serotonin, and adrenocorticotropic hormone.

AB - We describe a 42-year-old man with von Hippel-Lindau disease and islet cell tumor of the pancreas. He had retinal and cerebellar hemangioblastomas. His sister had pheochromocytoma. A pancreatic tumor was detected by ultrasonography at his periodical medical checkup. Contrast enhanced computed tomography and abdominal angiography revealed a hypervascular tumor in the pancreatic head. Histological examination of the resected tumor revealed characteristics of islet cell tumor of the pancreas, which was positive for chromogranin- A, S-100 protein, and pancreatic polypeptide, but was negative for insulin, gastrin, glucagon, somatostatin, vasoactive intestinal peptide, serotonin, and adrenocorticotropic hormone.

KW - Hemangioblastoma

KW - Pancreatic polypeptide producing tumor

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DO - 10.2169/internalmedicine.37.295

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AN - SCOPUS:0032015650

SN - 0918-2918

VL - 37

SP - 295

EP - 299

JO - Internal Medicine

JF - Internal Medicine

IS - 3

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Islet Cell Tumor in von Hippel-Lindau Disease

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