@article{3b9f70a3f1d541cab17cc13da9926baa,
title = "Isolation and expression patterns of genes for three angiopoietin-like proteins, Angptl1, 2 and 6 in zebrafish",
abstract = "Angiopoietin-like proteins (Angptls) are known to possess biological activities not only in the vascular system, but in the other mammalian tissues; however, their expression patterns and function in embryogenesis have not been extensively characterized. Here, we identify three zebrafish genes (Zangptl1, Zangptl2 and Zangptl6) highly homologous to mammalian Angptl1/ARP1, Angptl2/ARP2 and Angptl6/AGF, and describe their adult and embryonic temporal and spatial expression patterns. Zangptl1 is expressed faintly in the somites, while Zangptl2 is first detected in the yolk sac extension, spinal cord and branchial arches and is later expressed in the liver primordium and pectoral fin buds. Zangptl6 is expressed in the notochord. In addition to its embryonic expression, Zangptl2 is induced in adult fish during fin regeneration.",
keywords = "AGF, ARP, ARP1, ARP2, Angiopoietin, Angptl, Angptl1, Angptl2, Angptl6, Blastema, Branchial arch, Danio rerio, Fin bud, Fin regeneration, Liver, Notochord, Somite, Spinal cord, Yolk sac extension, Zebrafish",
author = "Yoshiaki Kubota and Yuichi Oike and Shinya Satoh and Yoko Tabata and Yuichi Niikura and Tohru Morisada and Masaki Akao and Takashi Urano and Yasuhiro Ito and Takeshi Miyamoto and Sumiko Watanabe and Toshio Suda",
note = "Funding Information: This work was supported by Grants-in-Aid from Human Frontier Science Promotion (HFSP) and the Ministry of Education, Culture, Sports, Science and Technology of Japan, by a Research Grant from the Mochida Memorial Foundation for Medical and Pharmaceutical Research, by a research grant from the Nateglinide Memorial Toyoshima Research and Education Fund and by a Keio University Grant-in-Aid for Encouragement of Young Medical Students.",
year = "2005",
month = jun,
doi = "10.1016/j.modgep.2005.02.006",
language = "English",
volume = "5",
pages = "679--685",
journal = "Gene Expression Patterns",
issn = "1567-133X",
publisher = "Elsevier",
number = "5",
}