Isolation of C11 cyclopentenones from two didemnid species, Lissoclinum sp. and Diplosoma sp.

Takayuki Ogi; Palupi Margiastuti; Toshiaki Teruya; Junsei Taira; Kiyotake Suenaga; Katsuhiro Ueda

doi:10.3390/md7040816

Isolation of C₁₁ cyclopentenones from two didemnid species, Lissoclinum sp. and Diplosoma sp.

Takayuki Ogi, Palupi Margiastuti, Toshiaki Teruya, Junsei Taira, Kiyotake Suenaga, Katsuhiro Ueda

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研究成果: Article › 査読

22 被引用数 (Scopus)

抄録

A series of new C₁₁ cyclopentenones 1-7 was isolated, together with four known metabolites 9/10, 12 and 13, from the extract of the didemnid ascidian Lissoclinum sp. The other didemnid ascidian Diplosoma sp. contained didemnenones 1, 2 and 5, and five known metabolites 8-12. The structures of 1-7 were elucidated by spectroscopic analyses. Cytotoxicity of the isolated compounds was evaluated against three human cancer cell lines (HCT116, A431 and A549).

本文言語	English
ページ（範囲）	816-832
ページ数	17
ジャーナル	Marine Drugs
巻	7
号	4
DOI	https://doi.org/10.3390/md7040816
出版ステータス	Published - 2009 12月

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10.3390/md7040816

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引用スタイル

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title = "Isolation of C11 cyclopentenones from two didemnid species, Lissoclinum sp. and Diplosoma sp.",

abstract = "A series of new C11 cyclopentenones 1-7 was isolated, together with four known metabolites 9/10, 12 and 13, from the extract of the didemnid ascidian Lissoclinum sp. The other didemnid ascidian Diplosoma sp. contained didemnenones 1, 2 and 5, and five known metabolites 8-12. The structures of 1-7 were elucidated by spectroscopic analyses. Cytotoxicity of the isolated compounds was evaluated against three human cancer cell lines (HCT116, A431 and A549).",

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AU - Taira, Junsei

AU - Suenaga, Kiyotake

AU - Ueda, Katsuhiro

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AB - A series of new C11 cyclopentenones 1-7 was isolated, together with four known metabolites 9/10, 12 and 13, from the extract of the didemnid ascidian Lissoclinum sp. The other didemnid ascidian Diplosoma sp. contained didemnenones 1, 2 and 5, and five known metabolites 8-12. The structures of 1-7 were elucidated by spectroscopic analyses. Cytotoxicity of the isolated compounds was evaluated against three human cancer cell lines (HCT116, A431 and A549).

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KW - Cytotoxicity

KW - Didemnenone

KW - Diplosoma

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