Isolation of monovalerianester a, an inhibitor of fat accumulation, from valeriana fauriei

Keiji Yuki; Mariko Ikeda; Shosuke Yoshida; Osamu Ohno; Kiyotake Suenaga; Kaoru Yamada; Daisuke Uemura; Kenji Miyamoto

doi:10.1177/1934578x1501000801

Isolation of monovalerianester a, an inhibitor of fat accumulation, from valeriana fauriei

Keiji Yuki, Mariko Ikeda, Shosuke Yoshida, Osamu Ohno, Kiyotake Suenaga, Kaoru Yamada, Daisuke Uemura, Kenji Miyamoto

研究成果: Article › 査読

3 被引用数 (Scopus)

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The rhizomes and roots of Valeriana fauriei were extracted with 80% aqueous ethanol. This extract was found to exhibit potent inhibitory effects on fat accumulation in 3T3-L1 murine adipocytes. After several steps of chromatographic purification, we succeeded in identifying monovalerianester A as an inhibitor of fat accumulation. Thus, monovalerianester A and the crude extract of the rhizomes and roots of V. fauriei may have therapeutic potential for the treatment of obesity.

本文言語	English
ページ（範囲）	1333-1334
ページ数	2
ジャーナル	Natural product communications
巻	10
号	8
DOI	https://doi.org/10.1177/1934578x1501000801
出版ステータス	Published - 2015 8月

ASJC Scopus subject areas

薬理学
植物科学
創薬
補完代替医療

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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10.1177/1934578x1501000801

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abstract = "The rhizomes and roots of Valeriana fauriei were extracted with 80% aqueous ethanol. This extract was found to exhibit potent inhibitory effects on fat accumulation in 3T3-L1 murine adipocytes. After several steps of chromatographic purification, we succeeded in identifying monovalerianester A as an inhibitor of fat accumulation. Thus, monovalerianester A and the crude extract of the rhizomes and roots of V. fauriei may have therapeutic potential for the treatment of obesity.",

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AU - Yuki, Keiji

AU - Ikeda, Mariko

AU - Yoshida, Shosuke

AU - Ohno, Osamu

AU - Suenaga, Kiyotake

AU - Yamada, Kaoru

AU - Uemura, Daisuke

AU - Miyamoto, Kenji

PY - 2015/8

Y1 - 2015/8

N2 - The rhizomes and roots of Valeriana fauriei were extracted with 80% aqueous ethanol. This extract was found to exhibit potent inhibitory effects on fat accumulation in 3T3-L1 murine adipocytes. After several steps of chromatographic purification, we succeeded in identifying monovalerianester A as an inhibitor of fat accumulation. Thus, monovalerianester A and the crude extract of the rhizomes and roots of V. fauriei may have therapeutic potential for the treatment of obesity.

AB - The rhizomes and roots of Valeriana fauriei were extracted with 80% aqueous ethanol. This extract was found to exhibit potent inhibitory effects on fat accumulation in 3T3-L1 murine adipocytes. After several steps of chromatographic purification, we succeeded in identifying monovalerianester A as an inhibitor of fat accumulation. Thus, monovalerianester A and the crude extract of the rhizomes and roots of V. fauriei may have therapeutic potential for the treatment of obesity.

KW - 3T3-L1 murine adipocytes

KW - Fat accumulation

KW - Inhibitor

KW - Monovalerianester A

KW - Valeriana fauriei

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Isolation of monovalerianester a, an inhibitor of fat accumulation, from valeriana fauriei

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ASJC Scopus subject areas

UN SDG

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