LIM homeobox 8 (Lhx8) is a key regulator of the cholinergic neuronal function via a tropomyosin receptor kinase A (TrkA)-mediated positive feedback loop

Takeyasu Tomioka; Takuya Shimazaki; Toshihiko Yamauchi; Toru Oki; Makoto Ohgoh; Hideyuki Okano

doi:10.1074/jbc.M113.494385

LIM homeobox 8 (Lhx8) is a key regulator of the cholinergic neuronal function via a tropomyosin receptor kinase A (TrkA)-mediated positive feedback loop

Takeyasu Tomioka, Takuya Shimazaki, Toshihiko Yamauchi, Toru Oki, Makoto Ohgoh, Hideyuki Okano

生理学

研究成果: Article › 査読

13 被引用数 (Scopus)

抄録

Background: LIM homeobox 8 (Lhx8) functions in the differentiation of cholinergic neurons. Results: Lhx8 regulates functions of cholinergic neurons by modulating tropomyosin receptor kinaseA(TrkA) expression. Lhx8 expression and function are regulated by NGF. Conclusion: Lhx8 is a mediator of NGF signaling for the regulation of cholinergic functions.

本文言語	English
ページ（範囲）	1000-1010
ページ数	11
ジャーナル	Journal of Biological Chemistry
巻	289
号	2
DOI	https://doi.org/10.1074/jbc.M113.494385
出版ステータス	Published - 2014 1月 10

ASJC Scopus subject areas

生化学
分子生物学
細胞生物学

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10.1074/jbc.M113.494385

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引用スタイル

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