TY - JOUR
T1 - Management of elderly ulcerative colitis in Japan
AU - Higashiyama, Masaaki
AU - Sugita, Akira
AU - Koganei, Kazutaka
AU - Wanatabe, Kenji
AU - Yokoyama, Yoko
AU - Uchino, Motoi
AU - Nagahori, Masakazu
AU - Naganuma, Makoto
AU - Bamba, Shigeki
AU - Kato, Shingo
AU - Takeuchi, Ken
AU - Omori, Teppei
AU - Takagi, Tomohisa
AU - Matsumoto, Satohiro
AU - Nagasaka, Mitsuo
AU - Sagami, Shintaro
AU - Kitamura, Kazuya
AU - Katsurada, Takehiko
AU - Sugimoto, Ken
AU - Takatsu, Noritaka
AU - Saruta, Masayuki
AU - Sakurai, Toshiyuki
AU - Watanabe, Kazuhiro
AU - Nakamura, Shiro
AU - Suzuki, Yasuo
AU - Hokari, Ryota
N1 - Funding Information:
Acknowledgements This research was supported by Research on Intractable Disease, Health and Labour Sciences Research Grants from the Ministry of Health, Labour and Welfare, Japan.
Publisher Copyright:
© 2019, Japanese Society of Gastroenterology.
PY - 2019/7/12
Y1 - 2019/7/12
N2 - Japan has the largest aging society, where many elderly people have intractable diseases including ulcerative colitis (UC). Along with the increasing total number of UC patients, the number of elderly UC patients has also been increasing and will continue to do so in the future. Although the clinical features and natural history of UC in the elderly have many similarities with UC in the non-elderly population, age-specific concerns including comorbidities, immunological dysfunction, and polypharmacy make the diagnosis and management of elderly UC challenging compared to UC in non-elderly patients. Based on increasing data related to elderly UC patients from Japan, as well as other countries, we reviewed the epidemiology, clinical course, differential diagnosis, management of comorbidities, surveillance, medical therapy, and surgery of UC in the elderly.
AB - Japan has the largest aging society, where many elderly people have intractable diseases including ulcerative colitis (UC). Along with the increasing total number of UC patients, the number of elderly UC patients has also been increasing and will continue to do so in the future. Although the clinical features and natural history of UC in the elderly have many similarities with UC in the non-elderly population, age-specific concerns including comorbidities, immunological dysfunction, and polypharmacy make the diagnosis and management of elderly UC challenging compared to UC in non-elderly patients. Based on increasing data related to elderly UC patients from Japan, as well as other countries, we reviewed the epidemiology, clinical course, differential diagnosis, management of comorbidities, surveillance, medical therapy, and surgery of UC in the elderly.
KW - Elderly
KW - Inflammatory bowel disease
KW - Management
KW - Ulcerative colitis
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U2 - 10.1007/s00535-019-01580-y
DO - 10.1007/s00535-019-01580-y
M3 - Review article
C2 - 31025187
AN - SCOPUS:85065120994
SN - 0944-1174
VL - 54
SP - 571
EP - 586
JO - Journal of gastroenterology
JF - Journal of gastroenterology
IS - 7
ER -