Metabolomics Analysis of OPLL Patients

Takashi Tsuji, Morio Matsumoto

研究成果: Chapter

抄録

Metabolomics is one of the “omics” technologies and is a comprehensive analysis of small molecule metabolites. The metabolomics is located at the downstream end of “omics” research; therefore, this research platform is most closely related to phenotype among other “omics” research. Recently, we compared the differences of metabolite profiling between patients with ossification of the posterior longitudinal ligament (OPLL) and control subjects for the first time and detected 259 metabolites. Among the 259 metabolites, some metabolites were significantly larger in OPLL group, even in analyses excluding patients with diabetes mellitus and hyperlipidemia. Although this research field is still in development, these results of the present study could lead to new insights into clarifying the molecular pathomechanisms of OPLL.

本文言語English
ホスト出版物のタイトルOPLL
ホスト出版物のサブタイトルOssification of the Posterior Longitudinal Ligament: Third Edition
出版社Springer Singapore
ページ89-97
ページ数9
ISBN(電子版)9789811538551
ISBN(印刷版)9789811538544
DOI
出版ステータスPublished - 2020 1月 1

ASJC Scopus subject areas

  • 医学一般

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