Molecular design, chemical synthesis, and evaluation of novel anthracene derivatives as a new family of protein photocleavers

Masashi Hasegawa, Akane Suzuki, Shuichi Matsumura, Kazunobu Toshima

研究成果: Article査読

14 被引用数 (Scopus)

抄録

The newly designed and synthesized artificial anthracene derivatives possessing a deoxyamino sugar effectively and randomly cleaved proteins, such as bovine serum albumin (BSA) and hen egg lysozyme (Lyso), during photoirradiation using a long wavelength UV light (365 nm) without any further additives. Furthermore, it was found that the cleaving ability of anthracene could be improved by the attachment of a suitable substituent into anthracene core skeleton.

本文言語English
ページ(範囲)169-174
ページ数6
ジャーナルScience and Technology of Advanced Materials
7
2
DOI
出版ステータスPublished - 2006 3月

ASJC Scopus subject areas

  • 材料科学(全般)

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