Monoclonal antibodies recognising pol and env proteins of mammalian retroviruses

Naoyuki Nishimura, Shingo Kato, Hiromichi Ishikawa, Toshiya Takano

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Mouse monoclonal antibodies were generated for three 20- to 23-mer synthetic peptides whose amino acid sequences were highly conserved in the pol or env regions of 14 mammalian and two avian retroviruses. By Western-blot analysis, these antibodies recognised the epitopes in major and minor pol or env proteins of six mammalian type-C and -D retroviruses. One of the anti-env monoclonal antibodies was found to recognise all the env transmembrane proteins of six mammalian retroviruses examined.

本文言語English
ページ(範囲)112-116
ページ数5
ジャーナルIntervirology
34
2
DOI
出版ステータスPublished - 1992

ASJC Scopus subject areas

  • ウイルス学
  • 感染症

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