TY - JOUR
T1 - Multiple Factors Causing Myopia and the Possible Treatments
T2 - A Mini Review
AU - Shinojima, Ari
AU - Negishi, Kazuno
AU - Tsubota, Kazuo
AU - Kurihara, Toshihide
N1 - Funding Information:
This work was supported by Tsubota Laboratory, Inc. The funding body took part in interpretation of data.
Publisher Copyright:
Copyright © 2022 Shinojima, Negishi, Tsubota and Kurihara.
PY - 2022/5/10
Y1 - 2022/5/10
N2 - The myopia epidemic has become a global public health problem. Although myopia is progressing worldwide, the recent coronavirus infections 2019 (COVID-19) outbreak has spurred myopia progression. The current evidence-based treatments for humans are atropine eye drops, optical treatment with defocus, use of orthokeratology, extending proximity working distance, pausing from near work every half hour and increased time outside the home. Studies on myopia using animal models have been conducted for more than 40 years. In recent years, new mechanisms of myopia suppression have been revealed from animal experiments such as inflammation control, intraocular pressure control, light control, and the activity of early growth response protein 1 control. This mini-review provides a summary of the scientific evidence currently available on the control of myopia, and the possible treatments mitigating myopia.
AB - The myopia epidemic has become a global public health problem. Although myopia is progressing worldwide, the recent coronavirus infections 2019 (COVID-19) outbreak has spurred myopia progression. The current evidence-based treatments for humans are atropine eye drops, optical treatment with defocus, use of orthokeratology, extending proximity working distance, pausing from near work every half hour and increased time outside the home. Studies on myopia using animal models have been conducted for more than 40 years. In recent years, new mechanisms of myopia suppression have been revealed from animal experiments such as inflammation control, intraocular pressure control, light control, and the activity of early growth response protein 1 control. This mini-review provides a summary of the scientific evidence currently available on the control of myopia, and the possible treatments mitigating myopia.
KW - Asian
KW - anthropometrics
KW - axial length (AL)
KW - myopia
KW - treatments
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U2 - 10.3389/fpubh.2022.897600
DO - 10.3389/fpubh.2022.897600
M3 - Review article
C2 - 35619815
AN - SCOPUS:85130700853
SN - 2296-2565
VL - 10
JO - Frontiers in Public Health
JF - Frontiers in Public Health
M1 - 897600
ER -
