TY - GEN
T1 - Optical property measurement of thin superficial tissue by using time-resolved spectroscopy
AU - Tanaka, Kenji
AU - Tanikawa, Yukari
AU - Araki, Ryuichiro
AU - Yamada, Yukio
AU - Okada, Eiji
N1 - Funding Information:
This work was partly supported by grant-in-aid for the 21st century center of excellence for optical and electronics device technology for access network from ministry of education culture, sport , science and technology in Japan. The authors thank NTT Mobile Communications Network, I nc. for allowance of the travel grant.
Publisher Copyright:
© 2003 SPIE-OSA.
PY - 2003
Y1 - 2003
N2 - Recently, non-invasive diagnostic devices using infrared light have been developed and widely use for clinical applications. To develop these devices, optical properties of biological tissue are necessary. We proposed a new optical measurement method. By using time-resolved reflectance spectroscopy and Monte Carlo simulation for the analysis of light propagation in sample, it is considered that this new method is able to measure the optical properties of small biological tissues in vivo. In this study, we investigated the possible optical property measurements of a superficial layer using this new method. As the later part of the profile of time-resolved reflectance is influenced by the optical property of the deeper layer, a time-gating technique is necessary for the measurement of the optical properties of only the superficial layer in order to use the early profile of the time-resolved reflectance measurement. The function f(t), which is described in the new method, is used for evaluation of the measurement of the superficial layer. We suggest that by using the time-gating technique for the new method and a small source-detector spacing, the optical properties of the superficial layer with a thickness is more than source-detector spacing, can be obtained.
AB - Recently, non-invasive diagnostic devices using infrared light have been developed and widely use for clinical applications. To develop these devices, optical properties of biological tissue are necessary. We proposed a new optical measurement method. By using time-resolved reflectance spectroscopy and Monte Carlo simulation for the analysis of light propagation in sample, it is considered that this new method is able to measure the optical properties of small biological tissues in vivo. In this study, we investigated the possible optical property measurements of a superficial layer using this new method. As the later part of the profile of time-resolved reflectance is influenced by the optical property of the deeper layer, a time-gating technique is necessary for the measurement of the optical properties of only the superficial layer in order to use the early profile of the time-resolved reflectance measurement. The function f(t), which is described in the new method, is used for evaluation of the measurement of the superficial layer. We suggest that by using the time-gating technique for the new method and a small source-detector spacing, the optical properties of the superficial layer with a thickness is more than source-detector spacing, can be obtained.
KW - Monte Carlo simulation
KW - Optical property
KW - small volume
KW - superficial layer
KW - time-resolved spectroscopy
UR - https://www.scopus.com/pages/publications/85136114620
UR - https://www.scopus.com/pages/publications/85136114620#tab=citedBy
M3 - Conference contribution
AN - SCOPUS:85136114620
T3 - Optics InfoBase Conference Papers
SP - 315
EP - 324
BT - European Conference on Biomedical Optics, ECBO 2003
PB - Optica Publishing Group (formerly OSA)
T2 - European Conference on Biomedical Optics, ECBO 2003
Y2 - 22 June 2003
ER -