TY - JOUR
T1 - Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis
AU - Basnet, Purusotam
AU - Matsushige, Katsumichi
AU - Hase, Koji
AU - Kadota, Shigetoshi
AU - Namba, Tsuneo
PY - 1996/4
Y1 - 1996/4
N2 - Hepatoprotective activity guided chemical analyses led to the isolation of two dicaffeoyl quinic acid derivatives, methyl 3,4- di-O-caffeoyl quinate (1) and 3,4-di-O-caffeoyl quinic acid (2) from water extract of propolis, and their structures were determined by the use of 2D NMR. These compounds were stronger antihepatotoxic agents than glycyrrhizin.
AB - Hepatoprotective activity guided chemical analyses led to the isolation of two dicaffeoyl quinic acid derivatives, methyl 3,4- di-O-caffeoyl quinate (1) and 3,4-di-O-caffeoyl quinic acid (2) from water extract of propolis, and their structures were determined by the use of 2D NMR. These compounds were stronger antihepatotoxic agents than glycyrrhizin.
KW - 3,4-di-O-caffeoyl quinic acid
KW - hepatoprotective activity
KW - liver
KW - methyl 3,4-di-O-caffeoyl quinate
KW - propolis
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U2 - 10.1248/bpb.19.655
DO - 10.1248/bpb.19.655
M3 - Article
C2 - 9132180
AN - SCOPUS:0029984357
SN - 0918-6158
VL - 19
SP - 655
EP - 657
JO - Biological and Pharmaceutical Bulletin
JF - Biological and Pharmaceutical Bulletin
IS - 4
ER -