Preimplantation genetic diagnosis: An update on current technologies and ethical considerations

Kou Sueoka

研究成果: Review article査読

12 被引用数 (Scopus)


The aim of reproductive medicine is to support the birth of healthy children. Advances in assisted reproductive technologies and genetic analysis have led to the introduction of preimplantation genetic diagnosis (PGD) for embryos. Indications for PGD have been a major topic in the fields of ethics and law. Concerns vary by nation, religion, population, and segment, and the continued rapid development of new technologies. In contrast to the ethical augment, technology has been developing at an excessively rapid speed. The most significant recent technological development provides the ability to perform whole genome amplification and sequencing of single embryonic cells by microarray or next-generation sequencing methods. As new affordable technologies are introduced, patients are presented with a growing variety of PGD options. Simultaneously, the ethical guidelines for the indications for testing and handling of genetic information must also rapidly correspond to the changes.

ジャーナルReproductive Medicine and Biology
出版ステータスPublished - 2016 4月

ASJC Scopus subject areas

  • 生殖医学
  • 細胞生物学


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