TY - JOUR
T1 - Prospective Investigation of Surgical Outcomes after Anterior Decompression with Fusion and Laminoplasty for the Cervical Ossification of the Posterior Longitudinal Ligament
T2 - A Propensity Score Matching Analysis
AU - Yoshii, Toshitaka
AU - Morishita, Shingo
AU - Egawa, Satoru
AU - Sakai, Kenichiro
AU - Kusano, Kazuo
AU - Tsutsui, Shunji
AU - Hirai, Takashi
AU - Matsukura, Yu
AU - Wada, Kanichiro
AU - Katsumi, Keiichi
AU - Koda, Masao
AU - Kimura, Atsushi
AU - Furuya, Takeo
AU - Maki, Satoshi
AU - Nagoshi, Narihito
AU - Nishida, Norihiro
AU - Nagamoto, Yukitaka
AU - Oshima, Yasushi
AU - Ando, Kei
AU - Nakashima, Hiroaki
AU - Takahata, Masahiko
AU - Mori, Kanji
AU - Nakajima, Hideaki
AU - Murata, Kazuma
AU - Miyagi, Masayuki
AU - Kaito, Takashi
AU - Yamada, Kei
AU - Banno, Tomohiro
AU - Kato, Satoshi
AU - Ohba, Tetsuro
AU - Inami, Satoshi
AU - Fujibayashi, Shunsuke
AU - Katoh, Hiroyuki
AU - Kanno, Haruo
AU - Taneichi, Hiroshi
AU - Imagama, Shiro
AU - Kawaguchi, Yoshiharu
AU - Takeshita, Katsushi
AU - Matsumoto, Morio
AU - Yamazaki, Masashi
AU - Okawa, Atsushi
N1 - Funding Information:
This study was supported by Japan Agency for Medical Research and Development and Japanese Health Labour Sciences Research Grant. This study was approved by each institutional review board.
Publisher Copyright:
© 2022 by the authors.
PY - 2022/12
Y1 - 2022/12
N2 - The ideal surgical strategy for cervical ossification of the posterior longitudinal ligament (OPLL) remains controversial due to the lack of high-quality evidence. Herein, we prospectively investigated the surgical outcomes of anterior cervical decompression with fusion (ADF) and laminoplasty (LAMP) with cervical OPLL. Three hundred patients were included in this study (ADF: n = 89; LAMP: n = 211 patients), and propensity score matching yielded 67 pairs of patients with ADF and LAMP, in which clinical outcomes were compared. Crude analysis revealed that the ADF group showed greater neurological recovery in cervical Japanese Orthopedic Association scores at two years, compared with that in the LAMP group (53.1% vs. 44.3%, p = 0.037). The ratio of minimum clinically important difference (MCID) success was significantly greater in the ADF group (59.6% vs. 43.6%, p = 0.016). Multivariate analysis showed that the factors affecting MCID success were age, body mass index, duration of symptoms, and choice of ADF. In the 1:1 matched analysis, neurological improvement was more favorable in the ADF group (57.2%) compared to the LAMP group (46.8%) at two years (p = 0.049). However, perioperative complications, such as dysphagia and graft-related complications, were more common in the ADF group.
AB - The ideal surgical strategy for cervical ossification of the posterior longitudinal ligament (OPLL) remains controversial due to the lack of high-quality evidence. Herein, we prospectively investigated the surgical outcomes of anterior cervical decompression with fusion (ADF) and laminoplasty (LAMP) with cervical OPLL. Three hundred patients were included in this study (ADF: n = 89; LAMP: n = 211 patients), and propensity score matching yielded 67 pairs of patients with ADF and LAMP, in which clinical outcomes were compared. Crude analysis revealed that the ADF group showed greater neurological recovery in cervical Japanese Orthopedic Association scores at two years, compared with that in the LAMP group (53.1% vs. 44.3%, p = 0.037). The ratio of minimum clinically important difference (MCID) success was significantly greater in the ADF group (59.6% vs. 43.6%, p = 0.016). Multivariate analysis showed that the factors affecting MCID success were age, body mass index, duration of symptoms, and choice of ADF. In the 1:1 matched analysis, neurological improvement was more favorable in the ADF group (57.2%) compared to the LAMP group (46.8%) at two years (p = 0.049). However, perioperative complications, such as dysphagia and graft-related complications, were more common in the ADF group.
KW - anterior decompression and fusion
KW - laminoplasty
KW - minimum clinically important difference
KW - neurological recovery
KW - ossification of the posterior longitudinal ligament
KW - propensity score matching
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U2 - 10.3390/jcm11237012
DO - 10.3390/jcm11237012
M3 - Article
AN - SCOPUS:85143627730
SN - 2077-0383
VL - 11
JO - Journal of Clinical Medicine
JF - Journal of Clinical Medicine
IS - 23
M1 - 7012
ER -