@inproceedings{3ed39af50ec947798e55bf2bd17ca3cd,
title = "PULSATILE FLOW ANALYSIS AT BRANCHED POINT IN ECM-BASED ENDOTHELIAL VASCULAR MODEL UNDER MECHANICAL STRETCH",
abstract = "This paper describes a stretchable extracellular matrix (ECM)-based in vitro endothelial vascular model with branched channels that can reproduce mechanically driven pulsatile flow. We imaged and analyzed the pulsatile flow at the branched points that are unique structures of blood vessels. The analysis revealed characteristic flow streams to the cultured endothelial cells near the branched points. We believe that our system would reveal the complex mechanical cellular response in blood vessels and enable the construction of mature in vitro vascular tissues.",
keywords = "ECM Microchannel, Endothelial Cell, Mechanical Stimulus, Perfusion, Pulsatile Flow, Stretching",
author = "Jumpei Muramatsu and Michinao Hashimoto and Shigenori Miura and Hiroaki Onoe",
note = "Funding Information: This work was partly supported by Grant-in Aid for Scientific Research (B) (19H04440) from Japan Society for the Promotion of Science (JSPS), Japan. M.H. acknowledges the Ministry of Education (MOE), Singapore, for the project funding (MOE2019-T2-2-192). Publisher Copyright: {\textcopyright} 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.; 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 ; Conference date: 10-10-2021 Through 14-10-2021",
year = "2021",
language = "English",
series = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Chemical and Biological Microsystems Society",
pages = "305--306",
booktitle = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
}