Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation

Takeshi Fukawa; Koji Takematsu; Kotaro Oka; Nobuyuki Miyahara; Sachiko Koike; Koichi Ando; Hirosuke Kobayashi; Kazuo Tanishita

Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation

Takeshi Fukawa, Koji Takematsu, Kotaro Oka, Nobuyuki Miyahara, Sachiko Koike, Koichi Ando, Hirosuke Kobayashi, Kazuo Tanishita

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研究成果: Article › 査読

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We measured directly the partial pressure of oxygen (pO₂) in new fibrosarcoma (NFSa) tumors grown in C3H/He mice using microcoaxial O₂ electrodes in vivo. The pO₂ in tumors was monitored after a single dose of X-ray or carbon-12 irradiation. After irradiation, tumor volume temporally shrinked, and pO₂ simultaneously increased. Carbon-12 irradiation reoxygenated tumors between the 1st and 9th day after the irradiation, while x-ray irradiation reoxygenated tumors between the 3rd and 8th day. We found that reoxygenation period after carbon-12 irradiation started earlier and continued longer than X-ray irradiation.

本文言語	English
ページ（範囲）	371-372
ページ数	2
ジャーナル	American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
巻	39
出版ステータス	Published - 1998 12月 1

ASJC Scopus subject areas

工学（全般）

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title = "Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation",

abstract = "We measured directly the partial pressure of oxygen (pO2) in new fibrosarcoma (NFSa) tumors grown in C3H/He mice using microcoaxial O2 electrodes in vivo. The pO2 in tumors was monitored after a single dose of X-ray or carbon-12 irradiation. After irradiation, tumor volume temporally shrinked, and pO2 simultaneously increased. Carbon-12 irradiation reoxygenated tumors between the 1st and 9th day after the irradiation, while x-ray irradiation reoxygenated tumors between the 3rd and 8th day. We found that reoxygenation period after carbon-12 irradiation started earlier and continued longer than X-ray irradiation.",

author = "Takeshi Fukawa and Koji Takematsu and Kotaro Oka and Nobuyuki Miyahara and Sachiko Koike and Koichi Ando and Hirosuke Kobayashi and Kazuo Tanishita",

year = "1998",

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language = "English",

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journal = "American Society of Mechanical Engineers, Bioengineering Division (Publication) BED",

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T1 - Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation

AU - Fukawa, Takeshi

AU - Takematsu, Koji

AU - Oka, Kotaro

AU - Miyahara, Nobuyuki

AU - Koike, Sachiko

AU - Ando, Koichi

AU - Kobayashi, Hirosuke

AU - Tanishita, Kazuo

PY - 1998/12/1

Y1 - 1998/12/1

N2 - We measured directly the partial pressure of oxygen (pO2) in new fibrosarcoma (NFSa) tumors grown in C3H/He mice using microcoaxial O2 electrodes in vivo. The pO2 in tumors was monitored after a single dose of X-ray or carbon-12 irradiation. After irradiation, tumor volume temporally shrinked, and pO2 simultaneously increased. Carbon-12 irradiation reoxygenated tumors between the 1st and 9th day after the irradiation, while x-ray irradiation reoxygenated tumors between the 3rd and 8th day. We found that reoxygenation period after carbon-12 irradiation started earlier and continued longer than X-ray irradiation.

AB - We measured directly the partial pressure of oxygen (pO2) in new fibrosarcoma (NFSa) tumors grown in C3H/He mice using microcoaxial O2 electrodes in vivo. The pO2 in tumors was monitored after a single dose of X-ray or carbon-12 irradiation. After irradiation, tumor volume temporally shrinked, and pO2 simultaneously increased. Carbon-12 irradiation reoxygenated tumors between the 1st and 9th day after the irradiation, while x-ray irradiation reoxygenated tumors between the 3rd and 8th day. We found that reoxygenation period after carbon-12 irradiation started earlier and continued longer than X-ray irradiation.

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AN - SCOPUS:0032302996

SN - 1071-6947

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JO - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

JF - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

ER -

Reoxygenation in tumor tissues after X-ray or carbon-12 irradiation

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