Scientific advances in lung cancer 2015

Anne S. Tsao; Giorgio V. Scagliotti; Paul A. Bunn; David P. Carbone; Graham W. Warren; Chunxue Bai; Harry J. De Koning; A. Uraujh Yousaf-Khan; Annette McWilliams; Ming Sound Tsao; Prasad S. Adusumilli; Ramón Rami-Porta; Hisao Asamura; Paul E. Van Schil; Gail E. Darling; Suresh S. Ramalingam; Daniel R. Gomez; Kenneth E. Rosenzweig; Stefan Zimmermann; Solange Peters; Sai Hong Ignatius Ou; Thanyanan Reungwetwattana; Pasi A. Jänne; Tony S. Mok; Heather A. Wakelee; Robert Pirker; Julien Mazières; Julie R. Brahmer; Yang Zhou; Roy S. Herbst; Vassiliki A. Papadimitrakopoulou; Mary W. Redman; Murry W. Wynes; David R. Gandara; Ronan J. Kelly; Fred R. Hirsch; Harvey I. Pass

doi:10.1016/j.jtho.2016.03.012

Scientific advances in lung cancer 2015

Anne S. Tsao, Giorgio V. Scagliotti, Paul A. Bunn, David P. Carbone, Graham W. Warren, Chunxue Bai, Harry J. De Koning, A. Uraujh Yousaf-Khan, Annette McWilliams, Ming Sound Tsao, Prasad S. Adusumilli, Ramón Rami-Porta, Hisao Asamura, Paul E. Van Schil, Gail E. Darling, Suresh S. Ramalingam, Daniel R. Gomez, Kenneth E. Rosenzweig, Stefan Zimmermann, Solange PetersSai Hong Ignatius Ou, Thanyanan Reungwetwattana, Pasi A. Jänne, Tony S. Mok, Heather A. Wakelee, Robert Pirker, Julien Mazières, Julie R. Brahmer, Yang Zhou, Roy S. Herbst, Vassiliki A. Papadimitrakopoulou, Mary W. Redman, Murry W. Wynes, David R. Gandara, Ronan J. Kelly, Fred R. Hirsch, Harvey I. Pass

外科学(呼吸器)

研究成果: Review article › 査読

215 被引用数 (Scopus)

抄録

Lung cancer continues to be a major global health problem; the disease is diagnosed in more than 1.6 million new patients each year. However, significant progress is underway in both the prevention and treatment of lung cancer. Lung cancer therapy has now emerged as a "role model" for precision cancer medicine, with several important therapeutic breakthroughs occurring during 2015. These advances have occurred primarily in the immunotherapy field and in treatments directed against tumors harboring specific oncogenic drivers. Our knowledge about molecular mechanisms for oncogene-driven tumors and about resistance to targeted therapies has increased quickly over the past year. As a result, several regulatory approvals of new agents that significantly improve survival and quality of life for patients with lung cancer who have advanced disease have occurred. The International Association for the Study of Lung Cancer has gathered experts in different areas of lung cancer research and management to summarize the most significant scientific advancements related to prevention and therapy of lung cancer during the past year.

本文言語	English
ページ（範囲）	613-638
ページ数	26
ジャーナル	Journal of Thoracic Oncology
巻	11
号	5
DOI	https://doi.org/10.1016/j.jtho.2016.03.012
出版ステータス	Published - 2016

ASJC Scopus subject areas

腫瘍学
呼吸器内科

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

文献へのアクセス

10.1016/j.jtho.2016.03.012

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引用スタイル

Tsao, A. S., Scagliotti, G. V., Bunn, P. A., Carbone, D. P., Warren, G. W., Bai, C., De Koning, H. J., Uraujh Yousaf-Khan, A., McWilliams, A., Tsao, M. S., Adusumilli, P. S., Rami-Porta, R., Asamura, H., Van Schil, P. E., Darling, G. E., Ramalingam, S. S., Gomez, D. R., Rosenzweig, K. E., Zimmermann, S., ... Pass, H. I. (2016). Scientific advances in lung cancer 2015. Journal of Thoracic Oncology, 11(5), 613-638. https://doi.org/10.1016/j.jtho.2016.03.012

Tsao, AS, Scagliotti, GV, Bunn, PA, Carbone, DP, Warren, GW, Bai, C, De Koning, HJ, Uraujh Yousaf-Khan, A, McWilliams, A, Tsao, MS, Adusumilli, PS, Rami-Porta, R, Asamura, H, Van Schil, PE, Darling, GE, Ramalingam, SS, Gomez, DR, Rosenzweig, KE, Zimmermann, S, Peters, S, Ou, SHI, Reungwetwattana, T, Jänne, PA, Mok, TS, Wakelee, HA, Pirker, R, Mazières, J, Brahmer, JR, Zhou, Y, Herbst, RS, Papadimitrakopoulou, VA, Redman, MW, Wynes, MW, Gandara, DR, Kelly, RJ, Hirsch, FR & Pass, HI 2016, 'Scientific advances in lung cancer 2015', Journal of Thoracic Oncology, vol. 11, no. 5, pp. 613-638. https://doi.org/10.1016/j.jtho.2016.03.012

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title = "Scientific advances in lung cancer 2015",

abstract = "Lung cancer continues to be a major global health problem; the disease is diagnosed in more than 1.6 million new patients each year. However, significant progress is underway in both the prevention and treatment of lung cancer. Lung cancer therapy has now emerged as a {"}role model{"} for precision cancer medicine, with several important therapeutic breakthroughs occurring during 2015. These advances have occurred primarily in the immunotherapy field and in treatments directed against tumors harboring specific oncogenic drivers. Our knowledge about molecular mechanisms for oncogene-driven tumors and about resistance to targeted therapies has increased quickly over the past year. As a result, several regulatory approvals of new agents that significantly improve survival and quality of life for patients with lung cancer who have advanced disease have occurred. The International Association for the Study of Lung Cancer has gathered experts in different areas of lung cancer research and management to summarize the most significant scientific advancements related to prevention and therapy of lung cancer during the past year.",

keywords = "Adjuvant chemotherapy, Biomarkers, Cancer prevention, Gene mutations, Immunotherapy, Lung cancer, Master protocols, Pathology, Radiotherapy, Screening, Smoking cessation, Staging, Surgery, Targeted therapy, Value of therapy",

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language = "English",

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pages = "613--638",

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AU - Scagliotti, Giorgio V.

AU - Bunn, Paul A.

AU - Carbone, David P.

AU - Warren, Graham W.

AU - Bai, Chunxue

AU - De Koning, Harry J.

AU - Uraujh Yousaf-Khan, A.

AU - McWilliams, Annette

AU - Tsao, Ming Sound

AU - Adusumilli, Prasad S.

AU - Rami-Porta, Ramón

AU - Asamura, Hisao

AU - Van Schil, Paul E.

AU - Darling, Gail E.

AU - Ramalingam, Suresh S.

AU - Gomez, Daniel R.

AU - Rosenzweig, Kenneth E.

AU - Zimmermann, Stefan

AU - Peters, Solange

AU - Ou, Sai Hong Ignatius

AU - Reungwetwattana, Thanyanan

AU - Jänne, Pasi A.

AU - Mok, Tony S.

AU - Wakelee, Heather A.

AU - Pirker, Robert

AU - Mazières, Julien

AU - Brahmer, Julie R.

AU - Zhou, Yang

AU - Herbst, Roy S.

AU - Papadimitrakopoulou, Vassiliki A.

AU - Redman, Mary W.

AU - Wynes, Murry W.

AU - Gandara, David R.

AU - Kelly, Ronan J.

AU - Hirsch, Fred R.

AU - Pass, Harvey I.

PY - 2016

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N2 - Lung cancer continues to be a major global health problem; the disease is diagnosed in more than 1.6 million new patients each year. However, significant progress is underway in both the prevention and treatment of lung cancer. Lung cancer therapy has now emerged as a "role model" for precision cancer medicine, with several important therapeutic breakthroughs occurring during 2015. These advances have occurred primarily in the immunotherapy field and in treatments directed against tumors harboring specific oncogenic drivers. Our knowledge about molecular mechanisms for oncogene-driven tumors and about resistance to targeted therapies has increased quickly over the past year. As a result, several regulatory approvals of new agents that significantly improve survival and quality of life for patients with lung cancer who have advanced disease have occurred. The International Association for the Study of Lung Cancer has gathered experts in different areas of lung cancer research and management to summarize the most significant scientific advancements related to prevention and therapy of lung cancer during the past year.

AB - Lung cancer continues to be a major global health problem; the disease is diagnosed in more than 1.6 million new patients each year. However, significant progress is underway in both the prevention and treatment of lung cancer. Lung cancer therapy has now emerged as a "role model" for precision cancer medicine, with several important therapeutic breakthroughs occurring during 2015. These advances have occurred primarily in the immunotherapy field and in treatments directed against tumors harboring specific oncogenic drivers. Our knowledge about molecular mechanisms for oncogene-driven tumors and about resistance to targeted therapies has increased quickly over the past year. As a result, several regulatory approvals of new agents that significantly improve survival and quality of life for patients with lung cancer who have advanced disease have occurred. The International Association for the Study of Lung Cancer has gathered experts in different areas of lung cancer research and management to summarize the most significant scientific advancements related to prevention and therapy of lung cancer during the past year.

KW - Adjuvant chemotherapy

KW - Biomarkers

KW - Cancer prevention

KW - Gene mutations

KW - Immunotherapy

KW - Lung cancer

KW - Master protocols

KW - Pathology

KW - Radiotherapy

KW - Screening

KW - Smoking cessation

KW - Staging

KW - Surgery

KW - Targeted therapy

KW - Value of therapy

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U2 - 10.1016/j.jtho.2016.03.012

DO - 10.1016/j.jtho.2016.03.012

M3 - Review article

C2 - 27013409

AN - SCOPUS:84969833490

SN - 1556-0864

VL - 11

SP - 613

EP - 638

JO - Journal of Thoracic Oncology

JF - Journal of Thoracic Oncology

IS - 5

ER -

Scientific advances in lung cancer 2015

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ASJC Scopus subject areas

UN SDG

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