Second-look endoscopy after endoscopic submucosal dissection for gastric neoplasms

Toshihiro Nishizawa, Hidekazu Suzuki, Satoshi Kinoshita, Osamu Goto, Takanori Kanai, Naohisa Yahagi

研究成果: Review article査読

22 被引用数 (Scopus)


Routine second-look endoscopy after gastric endoscopic submucosal dissection (ESD) remains controversial. The aim of the present study was to systematically evaluate the efficacy of second-look endoscopy for gastric ESD. PubMed, the Cochrane library, and the Igaku-chuo-zasshi database were searched in order to identify randomized trials eligible for inclusion in the systematic review. Data were combined to calculate a pooled odds ratio (OR) for developing post-ESD bleeding. The database search yielded three randomized trials (854 patients). Compared with second-look endoscopy, the pooled OR for post-ESD bleeding without second-look endoscopy was 0.69 (95% confidence interval [CI]: 0.38-1.26, P = 0.228), without significant heterogeneity. There were no significant differences between second-look endoscopy and no second-look endoscopy with regard to large tumor size (>20 mm). This systematic review and meta-analysis showed that second-look endoscopy had no advantage for the prevention of post-ESD bleeding in patients without a high risk of bleeding.

ジャーナルDigestive Endoscopy
出版ステータスPublished - 2015 3月 1

ASJC Scopus subject areas

  • 放射線学、核医学およびイメージング
  • 消化器病学


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