Short-term healing process of artificial ulcers after gastric endoscopic submucosal dissection

Osamu Goto, Mitsuhiro Fujishiro, Shinya Kodashima, Chihiro Minatsuki, Keiko Niimi, Satoshi Ono, Nobutake Yamamichi, Kazuhiko Koike

研究成果: Article査読

24 被引用数 (Scopus)


Background/Aims: The relationship between the appearance of an ulcer and postoperative bleeding after gastric endoscopic submucosal dissection (ESD) is not well understood. To explore this potential relationship, we retrospectively analyzed the short-term healing process of ESD. Methods: A total of 520 consecutive lesions in 434 patients seen between January 2004 and December 2009 were retrospectively investigated. At the second-look endoscopy, which occurred between 1 and 8 days after ESD, artificial ulcers were categorized into 6 patterns according to Forrest's classification: spurting bleeding, oozing bleeding, nonbleeding visible vessel, adherent clot, black base/spot, and clean base. From these data, a short-term healing model of the artificial ulcer was generated. Results: Ulcers were observed to change gradually from a bloody to a clean surface. The bleeding or non-bleeding visible vessel categories, which occurred in approximately one quarter of the ulcers within 3 days of ESD, were rarely observed 4 days after ESD. Conclusions: Ulcers that occur after gastric ESD heal in line with a specific time course, and it appears that most healing occurs without massive bleeding.

ジャーナルGut and Liver
出版ステータスPublished - 2011 9月

ASJC Scopus subject areas

  • 肝臓学
  • 消化器病学


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