Sonographic appearance of the submandibular glands in patients with immunoglobulin G4-related disease

Satomi Asai, Kenji Okami, Naoya Nakamura, Shuichi Shiraishi, Tomohiro Yamashita, Damdinsuren Anar, Hiromichi Matsushita, Hayato Miyachi

研究成果: Article査読

12 被引用数 (Scopus)

抄録

Swelling of the salivary glands is often an initial sign of immunoglobulin G4 (IgG4)-related disease or IgG4-related sclerosing/autoimmune disease. We encountered 2 patients with IgG4-related disease who showed swollen submandibular glands with a unique characteristic sonographic pattern. Bilateral submandibular glands of both patients were enlarged with a smooth contour. The internal echo texture indicated multiple hypoechoic foci scattered against a heterogeneous background, which characteristically appeared with a mottled or irregular netlike appearance. A histopathologic examination of a resected section showed multiple foci of dense infiltrated lymphoplasmacytic cells and lymph follicles encircled by fibrous bands. A mottled appearance in the sonographic findings of the submandibular glands suggests the characteristic of IgG4-related disease and can be helpful in the differential diagnosis at the initial manifestation.

本文言語English
ページ(範囲)489-493
ページ数5
ジャーナルJournal of Ultrasound in Medicine
31
3
DOI
出版ステータスPublished - 2012 3月 1
外部発表はい

ASJC Scopus subject areas

  • 放射線技術および超音波技術
  • 放射線学、核医学およびイメージング

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